Evidence map›Paper›PMID 26085910›Full record

ReviewWorld journal of hepatology2015

Current developments in pediatric liver transplantation.

Christina Hackl, Hans J Schlitt, Michael Melter, Birgit Knoppke, Martin Loss

Abstract readReview
In one paragraph

Review in World journal of hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  4. Review
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  8. Review
  9. Article
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  16. Observational
  17. Genome editing technologies to treat rare liver diseases.Translational gastroenterology and hepatology · 2020
    Review
  18. Split liver transplantation: Current developments.World journal of gastroenterology · 2018
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christina HacklChristina Hackl, Hans J Schlitt, Martin Loss, Department of Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
Hans J SchlittChristina Hackl, Hans J Schlitt, Martin Loss, Department of Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
Michael MelterChristina Hackl, Hans J Schlitt, Martin Loss, Department of Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
Birgit KnoppkeChristina Hackl, Hans J Schlitt, Martin Loss, Department of Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.
Martin LossChristina Hackl, Hans J Schlitt, Martin Loss, Department of Surgery, University Hospital Regensburg, 93053 Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 1953, the pioneer of human orthotopic liver transplantation (LT), Thomas E Starzl, was the first to attempt an orthotopic liver transplant into a 3 years old patient suffering from biliary atresia. Thus, the first LT in humans was attempted in a disease, which, up until today, remains the main indication for pediatric LT (pLT). During the last sixty years, refinements in diagnostics and surgical technique, the introduction of new immunosuppressive medications and improvements in perioperative pediatric care have established LT as routine procedure for childhood acute and chronic liver failure as well as inherited liver diseases. In contrast to adult recipients, pLT differs greatly in indications for LT, allocation practice, surgical technique, immunosuppression and post-operative life-long aftercare. Many aspects are focus of ongoing preclinical and clinical research. The present review gives an overview of current developments and the clinical outcome of pLT, with a focus on alternatives to full-size deceased-donor organ transplantation.

Indexed as

Biliary atresiaDeceased organ donationLiving donor liver transplantationPediatric liver transplantationSplit liver transplantation

Identifiers

PMID26085910
PMCPMC4462689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.