Evidence map›Paper›PMID 26085866›Full record

ArticleCanadian Urological Association journal = Journal de l'Association des urologues du Canada

Surgical management of stage T1 renal tumours at Canadian academic centres.

Luke T Lavallée, Simon Tanguay, Michael A Jewett, Lori Wood, Anil Kapoor, Ricardo A Rendon, Ronald B Moore, Louis Lacombe, Jun Kawakami, Stephen E Pautler and 7 more

Erratum issuedOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Canadian Urological Association journal = Journal de l'Association des urologues du Canada. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. The impact of robotic surgery access on the management of patients with clinical stage I kidney tumors.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024
    Article
  3. Derivation and validation of text search algorithms for renal and adrenal lesion identification in radiology text reports.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020
    Article
  4. Transplanting kidneys from donors with small renal masses - a strategy to expand the donor pool.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020
    Review
  5. Article
  6. Article
  7. Correction in figure.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2016
    Article
  8. Partial versus radical nephrectomy for renal tumours ≤7 cm: The debate continues.Canadian Urological Association journal = Journal de l'Association des urologues du Canada
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 2 countries.

Luke T LavalléeDivision of Urology, University of Ottawa, Ottawa, ON; ; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON;
Simon TanguayDivision of Urology, McGill University, Montreal, QC;
Michael A JewettDivision of Urology, University of Toronto, Toronto, ON;
Lori WoodDepartment of Medicine and Urology, Dalhousie University, Halifax, NS;
Anil KapoorDivision of Urology, McMaster University, Hamilton, ON;
Ricardo A RendonDepartment of Urology, Dalhousie University, Halifax, NS;
Ronald B MooreDivision of Urology, University of Alberta, Edmonton, AB;
Louis LacombeDivision of Urology, Université Laval, Quebec City, QC;
Jun KawakamiDivision of Urology, University of Calgary, Calgary, AB;
Stephen E PautlerDivision of Urology, Western University, London, ON;
Darrel E DrachenbergDivision of Urology, University of Manitoba, Winnipeg, MB;
Peter C BlackDepartment of Urologic Sciences, University of British Columbia, Vancouver, BC;
Jean-Baptiste LattoufDivision of Urology, Centre hospitalier de l'université de Montreal, Montreal, QC;
Christopher MorashDivision of Urology, University of Ottawa, Ottawa, ON;
Ilias CagiannosDivision of Urology, University of Ottawa, Ottawa, ON;
Zhihui LiuCancer Care Ontario, Toronto, Ontario, Canada.
Rodney H BreauDivision of Urology, University of Ottawa, Ottawa, ON; ; Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON;
University of Ottawa · CADalhousie University · CACancer Care Ontario · CACentre Hospitalier de l’Université de Montréal · CAMcGill University · CAMcMaster University · CAOttawa Hospital Research InstituteUniversité Laval · CAUniversity of Alberta · CAUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Manitoba · CAUniversity of Toronto · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe proportion of patients with stage 1 renal tumours receiving partial nephrectomy is considered a quality of care indicator. The objective of this study was to characterize surgical practice patterns at Canadian academic institutions for the treatment of these tumours.

methodsThe Canadian Kidney Cancer Information System (CKCis) is a multicentre collaboration of 13 academic institutions in Canada. All patients with pathologic stage T1 renal tumours in CKCis were identified. Descriptive statistics were performed to characterize practice patterns over time. Associations between patient, tumour, and treatment factors with the use of partial nephrectomy were determined.

resultsFrom 1988 to April 2014, 1453 patients with pathologic stage 1 renal tumours were entered in the CKCis database. Of these, 977 (67%) patients had pT1a tumours; of these, 765 (78%) received partial nephrectomy. Of the total number of patients (1453), 476 (33%) had pT1b tumours; of these, 204 (43%) received partial nephrectomy. The use of partial nephrectomy increased over time from 60% to 90% for pT1a tumours and 20% to 60% for pT1b tumours. Stage pT1b (relative risk [RR] 0.56, 95% confidence interval [CI] 0.50-0.63) and minimally invasive surgical approach (RR 0.78, 95% CI 0.73-0.84 for pT1a and RR 0.23, 95% CI 0.17-0.30 for pT1b) were associated with decreased use of partial nephrectomy. Most patient factors including age, gender, body mass index, hypertension, and renal function were not significantly associated with use of partial nephrectomy (p > 0.05).

conclusionAlmost all pT1a and most pT1b renal tumours managed surgically at academic centres in Canada receive partial nephrectomy. The use of partial versus radical nephrectomy appears to occur independently of patient age and comorbid status, which may indicate that urologists are performing partial nephrectomy whenever technically feasible based on tumour factors. Although the ideal proportion patients receiving partial nephrectomy cannot be determined, treatment distribution observed in this cohort may indicate an achievable case distribution among experienced surgeons.

Identifiers

PMID26085866
PMCPMC4455632
OpenAlexW2064915842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.