ArticleNuclear medicine and molecular imaging2015
Correlation of Primary Tumor FDG Uptake with Histopathologic Features of Advanced Gastric Cancer.
Article in Nuclear medicine and molecular imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Molecular Imaging in Gastric Cancer: [¹⁸F]FDG and Fibroblast Activation Protein-Targeted PET/CT.Journal of gastric cancer · 2026Review
- CT-based deep learning radiomics analysis for preoperative Lauren classification in gastric cancer and explore the tumor microenvironment.European journal of radiology open · 2025Article
- Evaluating the diagnostic performance of [European radiology · 2025Article
- Systematic review of diagnostic tools for peritoneal metastasis in gastric cancer-staging laparoscopy and its alternatives.World journal of gastrointestinal surgery · 2023Article
- Prognostic Value of [Cancers · 2023Article
- Prognostic value of the metabolic score obtained via [Scientific reports · 2022Article
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- Glucose metabolic profiles evaluated by PET associated with molecular characteristic landscape of gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022Article
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- Establishment of a [Journal of gastric cancer · 2020Article
- Clinicopathologic parameters associated with the FDG-avidity in staging of early gastric cancer using 18F-FDG PET.Medicine · 2019Observational
- Clinical implication of FDG uptake of bone marrow on PET/CT in gastric cancer patients with surgical resection.World journal of gastroenterology · 2017Article
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4 authors.
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Abstract
purposeHistopathologic features could affect the FDG uptake of primary gastric cancer and detection rate on FDG PET/CT. The aim of this study was to evaluate the FDG uptake of primary gastric cancer by correlating it with the histopathologic features of the tumors.
methodsFifty patients with locally advanced gastric adenocarcinoma who were referred for preoperative FDG-PET/CT scans were enrolled in this study. The detection rate of PET/CT and maximum standardized uptake values (SUVmax) of the primary tumor were compared using the WHO, Lauren, Ming and Borrmann classifications and tumor size and location.
resultsIn 45 of the 50 patients (90 %), the primary gastric tumors were detected by FDG PET/CT. On comparison using the WHO classification, the detection rate and SUVmax of the tubular type were significantly higher than those of the poorly cohesive type. On comparison using the Lauren and Ming classifications, the SUVmaxs of the intestinal type and expanding type were significantly higher than those of the diffuse and infiltrative type, respectively. On comparison using the Borrmann classification and tumor size and location, there was no significant difference in the detection rate and SUVmax of primary gastric tumors.
conclusionThis study demonstrates that the poorly cohesive type according to the WHO classification, diffuse type according to the Lauren classification and infiltrative type according to the Ming classification have low FDG uptake in patients with locally advanced gastric carcinoma. Understanding the relationship between primary tumor FDG uptake and histopathologic features would be helpful in detecting the primary tumor by FDG PET/CT in patients with gastric cancer.
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