Evidence map›Paper›PMID 26085848›Full record

ArticleStatistics in biosciences2015

Semiparametric Bayes local additive models for longitudinal data.

Zhaowei Hua, Hongtu Zhu, David B Dunson

Abstract read
In one paragraph

Article in Statistics in biosciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhaowei HuaDepartment of Biostatistics, University of North Carolina at Chapel Hill.
Hongtu ZhuDepartment of Biostatistics, University of North Carolina at Chapel Hill.
David B DunsonDepartment of Statistical Science, Duke University.

Funding

UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
Statistical Methods for Cancer Clinical TrialsP01CA142538 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVIDIAN, MARIE, KOSOROK, MICHAEL R · 2010 to 2019
$21.3M
Statistical Analysis of Biomedical Imaging Data in Curved SpaceR01MH086633 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2010 to 2018
$2.9M
Nonparametric Bayes Methods for Biomedical StudiesR01ES017240 · NIEHS · DUKE UNIVERSITY · PI DUNSON, DAVID BRIAN · 2009 to 2013
$1.2M
Longitudinal Analysis of Biomedical Imaging DataR21AG033387 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHU, HONGTU · 2009 to 2010
$334k
NCI NIH HHS P01 CA142538NCRR NIH HHS UL1 RR025747NIA NIH HHS R21 AG033387NIEHS NIH HHS R01 ES017240NIMH NIH HHS R01 MH086633
6 · The paper itself

Abstract

In longitudinal data analysis, there is great interest in assessing the impact of predictors on the time-varying trajectory in a response variable. In such settings, an important issue is to account for heterogeneity in the shape of the trajectory among subjects, while allowing the impact of the predictors to vary across subjects. We propose a flexible semiparametric Bayes approach for addressing this issue relying on a local partition process prior, which allows flexible local borrowing of information across subjects. Local hypothesis testing and credible bands are developed for the identification of time windows across which a predictor has a significant impact, while adjusting for multiple comparisons. Posterior computation proceeds via an efficient MCMC algorithm using the exact block Gibbs sampler. The methods are assessed using simulation studies and applied to a yeast cell-cycle gene expression data set.

Indexed as

Confidence bandFunctional dataGaussian processLocal partition processRandom effectsTime-varying coefficients

Identifiers

PMID26085848
PMCPMC4465815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.