Evidence map›Paper›PMID 26085693›Full record

ArticleTetrahedron letters2015

Temperature dependence of turnover in a Sc(OTf)

Charlie Fehl, Erin E Hirt, Sze-Wan Li, Jeffrey Aubé

Abstract read
In one paragraph

Article in Tetrahedron letters, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Charlie FehlUniversity of Kansas, Department of Medicinal Chemistry, Delbert M. Shankel Structural Biology Center, 2034 Becker Drive, Lawrence, KS 66047-3761, United States.
Erin E HirtUniversity of Kansas, Department of Medicinal Chemistry, Delbert M. Shankel Structural Biology Center, 2034 Becker Drive, Lawrence, KS 66047-3761, United States.
Sze-Wan LiUniversity of Kansas, Department of Medicinal Chemistry, Delbert M. Shankel Structural Biology Center, 2034 Becker Drive, Lawrence, KS 66047-3761, United States.
Jeffrey AubéUniversity of Kansas, Department of Medicinal Chemistry, Delbert M. Shankel Structural Biology Center, 2034 Becker Drive, Lawrence, KS 66047-3761, United States.
University of Kansas · US

Funding

TRAINING GRANT IN DYNAMIC ASPECTS OF CHEMICAL BIOLOGYT32GM008545 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI LAMB, AUDREY L · 1994 to 2019
$4.9M
NEW REACTIONS OF ALKYL AZIDES WITH KETONESR01GM049093 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI AUBE, JEFFREY · 1993 to 2008
$2.2M
NIGMS NIH HHS R01 GM049093NIGMS NIH HHS T32 GM008545
6 · The paper itself

Abstract

The intramolecular Schmidt reaction of ketones and tethered azides is an efficient method for the generation of amides and lactams. This reaction is catalyzed by Lewis acids, which tightly bind the strongly basic amide product and result in product inhibition. We report herein conditions to achieve a catalytic Schmidt reaction using substoichiometric amounts of the heat-stable Lewis acid Sc(OTf)

Indexed as

Intramolecular Schmidt reactionPolycyclic lactamsRing expansionScandium triflate catalysisTurnover

Identifiers

PMID26085693
PMCPMC4465195
OpenAlexW2076847050

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.