Evidence map›Paper›PMID 26085368›Full record

Trial reportScientific reports2015

Detection of trace metallic elements in oral lichenoid contact lesions using SR-XRF, PIXE, and XAFS.

Tomoko Sugiyama, Motohiro Uo, Takahiro Wada, Daisuke Omagari, Kazuo Komiyama, Serika Miyazaki, Chiya Numako, Tadahide Noguchi, Yoshinori Jinbu, Mikio Kusama and 1 more

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Tomoko SugiyamaDepartment of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical University, Tochigi, Japan.
Motohiro Uo1] Advanced Biomaterials Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan [2] Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.
Takahiro WadaAdvanced Biomaterials Department, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Daisuke OmagariDepartment of Pathology, Nihon University School of Dentistry, Tokyo, Japan.
Kazuo KomiyamaDepartment of Pathology, Nihon University School of Dentistry, Tokyo, Japan.
Serika MiyazakiGraduate School of Science, Chiba University, Chiba, Japan.
Chiya NumakoGraduate School of Science, Chiba University, Chiba, Japan.
Tadahide NoguchiDepartment of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical University, Tochigi, Japan.
Yoshinori JinbuDepartment of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical University, Tochigi, Japan.
Mikio KusamaDepartment of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical University, Tochigi, Japan.
Yoshiyuki MoriDepartment of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical University, Tochigi, Japan.
Jichi Medical University · JPChiba University · JPNihon University · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral lichen planus (OLP) and oral lichenoid contact lesions (OLCL) are chronic inflammatory mucocutaneous reactions with a risk of malignant transformation that alter the epithelium. OLP and OLCL have similar clinical and histopathological features and it is difficult to distinguish one from the other. Metallic restorations are suspected to generate OLCLs. Trace metal analysis of OLCL specimens may facilitate the discrimination of symptoms and identification of causative metallic restorations. The purpose of this study was to assess OLCL tissue samples for the prevalence of metallic elements derived from dental restorations, and to discriminate OLCL from OLP by using synchrotron radiation-excited X-ray fluorescence analysis (SR-XRF), particle-induced X-ray emission (PIXE), and X-ray absorption fine structure (XAFS). Typical elements of dental materials were detected in the OLCL, whereas no obvious element accumulation was detected in OLP and negative control specimens. The origin of the detected metallic elements was presumed to be dental alloys through erosion. Therefore, our findings support the feasibility of providing supporting information to distinguish OLCL from OLP by using elemental analysis.

Indexed as

AdultDental AlloysFemaleHumansLichen Planus, OralMaleMouth MucosaTrace ElementsDental AlloysTrace Elements

Identifiers

PMID26085368
PMCPMC4471725
OpenAlexW895906345

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.