Evidence map›Paper›PMID 26085168›Full record

ArticleJournal of virology2015

Host Range Restriction of Epstein-Barr Virus and Related Lymphocryptoviruses.

Janine Mühe, Fred Wang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janine MüheDepartment of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, and Department of Molecular Biology & Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Fred WangDepartment of Medicine, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, and Department of Molecular Biology & Immunobiology, Harvard Medical School, Boston, Massachusetts, USA fwang@research.bwh.harvard.edu.
Harvard University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
PATHOGENESIS OF EPSTEIN BARR VIRUS INFECTIONR01CA068051 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI WANG, FREDERICK C. · 1995 to 2014
$5.8M
Neutralizing Antibodies in Acute and Persistent Epstein-Barr Virus InfectionR01AI114557 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI WANG, FREDERICK C. · 2015 to 2019
$2.8M
NCI NIH HHS R01 CA068051NIAID NIH HHS R01 AI114557NIH HHS P51 OD011132
6 · The paper itself

Abstract

Epstein-Barr-related herpesviruses, or lymphocryptoviruses (LCV), naturally infect humans and nonhuman primates (NHP), but their host range is not well characterized. Using LCV and B cells from multiple species of Hominidae and Cercopithecidae, we show that LCV can immortalize B cells from some nonnative species but that growth transformation is restricted to B cells from their own family of hominoids or Old World NHP, suggesting a high degree of LCV adaptation to their natural primate host.

Indexed as

Host SpecificityAmino Acid SequenceAnimalsBase SequenceB-LymphocytesCercopithecidaeEpstein-Barr Virus Nuclear AntigensHerpesviridae InfectionsHerpesvirus 4, HumanHumansLymphocryptovirusMolecular Sequence DataMonkey DiseasesSequence AlignmentSequence Analysis, DNAViral ProteinsEBNA-2 protein, Human herpesvirus 4Epstein-Barr Virus Nuclear AntigensViral Proteins

Identifiers

PMID26085168
PMCPMC4524086
OpenAlexW1913587233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.