ArticleBMC oral health2015
Caries prevalence and impact on oral health-related quality of life in children with sickle cell disease: cross-sectional study.
Article in BMC oral health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- SOCIOECONOMIC AND NUTRITIONAL CHARACTERISTICS OF CHILDREN AND ADOLESCENTS WITH SICKLE CELL ANEMIA: A SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao PauloPooled it
- Association between sickle cell anaemia and dental caries among children in Nigeria.BMC oral health · 2025Article
- Impact of dental caries on the quality of life of children with sickle cell anaemia in Nigeria.Journal of public health in Africa · 2025Article
- Oral Health Status of People with Sickle Cell Disease at a Major Hospital in Cameroon.International journal of MCH and AIDS · 2025Article
- Article
- Dental Caries in Children with Sickle Cell Disease and Its Association with the Use of Hydroxyurea and Penicillin Prophylaxis in Dar Es Salaam.Pediatric health, medicine and therapeutics · 2024Article
- Quality of life in children and adolescents with blood coagulation disorders and hemoglobinopathies.Brazilian oral research · 2024Article
- Validating evidence for the knowledge, management and involvement of dentists in a dental approach to sickle-cell disease.Brazilian oral research · 2024Article
- Review
- Oral health-related quality of life in children with celiac disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Orofacial manifestations of sickle cell disease: implications for dental clinicians.British dental journal · 2021Article
- Oral health status and impact on the oral health-related quality of life of Egyptian children and early adolescents with type-1 diabetes: a case-control study.Clinical oral investigations · 2020Article
- Relationships of Dental Caries and Malocclusion with Oral Health-Related Quality of Life in Lithuanian Adolescents Aged 15 to 18 Years: A Cross-Sectional Study.International journal of environmental research and public health · 2020Article
- Oral health-related quality of life in children using the child perception questionnaire CPQ11-14: a review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2019Review
- Association between sickle cell disease and the oral health condition of children and adolescents.BMC oral health · 2018Article
- Dental tissues of sickle cell anemia and its impact on the quality of life related to oral health.Hematology, transfusion and cell therapyArticle
- Comment on: "Oral health-related quality of life in children and teens with sickle cell disease".Revista brasileira de hematologia e hemoterapiaArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildren with sickle cell disease (SCD) may present oral conditions that can compromise children's health even more. However, there is still no consensus on the association between SCD and dental caries. The aim of this study was to assess caries prevalence in children with sickle cell disease (SCD), and the association of dental caries with socioeconomic factors, disease severity, and oral-health related to quality of life (OHRQoL).
methodsThe sample was comprised of 106 children with SCD aged 8 to 14 years who were attending the Center for Hematology (Hemominas) in Belo Horizonte, Brazil. They were matched to 385 healthy peers. Data collection included interviews with guardians concerning SCD characteristics, and previous social and oral examinations to determine the caries prevalence. Caries prevalence as measured through the Decayed, Missing and Filled (dmft and DMFT) indices. OHRQoL was evaluated through the Brazilian versions of the Child Perceptions Questionnaires (CPQ8-10, and CPQ11-14 short-form version). Statistical analyses were performed using the chi-square test or Fisher`s exact test and the Mann Whitney test, as well as linear regression.
resultsThe DMFT index was 1.3 (SD: 2.1) in younger children with SCD and 1.5 (SD: 1.9) in SCD teens. Younger children with SCD had lower caries experience compared to healthy peers (p = .03). The experience of dental caries among teens with SCD was similar to healthy peers (p > 0.05). In addition, we did not see a significant difference on the mean overall scores of CPQ8-10 between SCD younger children and controls. There was no statistically significant difference in the mean overall scores of teens CPQ11-14 between SCD and the control group. Socioeconomic variables were not associated with dental caries in the participants with SCD. However, SCD severity was associated with higher DMFT indexes (p < 0.05).
conclusionsYounger children with SCD had a low experience of dental caries. The dental caries experience in teenagers with SCD was similar to their healthy peers. OHRQoL was similar between SCD participants and controls.
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