Evidence map›Paper›PMID 26084958›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2015

Assessment of Macular Peripapillary Nerve Fiber Layer and Choroidal Thickness Changes in Pregnant Women with Gestational Diabetes Mellitus, Healthy Pregnant Women, and Healthy Non-Pregnant Women.

Gokhan Acmaz, Mustafa Atas, Ahmet Gulhan, Banu Acmaz, Fatma Atas, Huseyin Aksoy, Gokmen Zararsiz, Gokcen Gokce

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Retinal and choroidal optical coherence tomography findings in gestational diabetes mellitus: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Pooled it
  2. Observational
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Enhancement of Choriocapillaris Visualization in En Face Swept-Source Optical Coherence Tomography Angiography Images.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  8. Article
  9. Comparative analysis of choroidal thickness in third trimester pregnant women.International journal of retina and vitreous · 2018
    Article
  10. The Effect of Oral Contraceptive Pills on the Macula, the Retinal Nerve Fiber Layer, and Choroidal Thickness.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  11. Review
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gokhan AcmazDepartment of Obstetrics and Gynecology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Mustafa AtasDepartment of Ophthalmology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Ahmet GulhanDepartment of Ophthalmology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Banu AcmazDepartment of Internal Medicine, Erciyes University School of Medicine, Kayseri, Turkey.
Fatma AtasDepartment of Obstetrics and Gynecology, Kayseri Education and Research Hospital, Kayseri, Turkey.
Huseyin AksoyDepartment of Obstetrics and Gynecology, Kayseri Military Hospital, Kayseri, Turkey.
Gokmen ZararsizDepartment of Statistics, Erciyes University School of Medicine, Kayseri, Turkey.
Gokcen GokceDepartment of Ophthalmology, Kayseri Military Hospital, Kayseri, Turkey.
Kayseri Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGestational diabetes mellitus (GDM) is a risk factor for the development of type II diabetes and it causes maternal and child morbidity. Screening for diabetic retinopathy (DR) is important because patients who develop DR have no symptoms until macular edema and/or proliferative diabetic retinopathy (PDR) are already present. The aim of this study was to determine the early retinal findings of GDM. MATERIAL AND

methodsThis study was conducted in a tertiary research center. We conducted a prospective cross-sectional study with 3 groups: Group 1 consisted of 36 pregnant women with GDM, Group 2 consisted of 24 healthy pregnant women, and Group 3 consisted of 38 healthy non-pregnant women of reproductive age. Spectralis optical coherence tomography (OCT) was used for the assessment. Macular, choroid, and retinal nerve fiber layer (RNFL) thicknesses were evaluated in patients with GDM and comparisons were made among pregnant women with GDM, healthy pregnant women, and healthy non-pregnant women for these parameters.

resultsThe nasal part of the RNFL was significantly thinner in the GDM group than in the healthy pregnant group. None of the patients had retinopathy or macular edema at the time of examination.

conclusionsDecreased nasal part of RNFL thickness may be the first retinal change in patients with GDM. Our study suggests that OCT should be performed for the patients with GDM for detection of early retinal changes associated with GDM.

Indexed as

AdultCase-Control StudiesChoroidCross-Sectional StudiesDiabetes, GestationalDiabetic RetinopathyFemaleHumansMacular EdemaNerve FibersOptic DiskPregnancyProspective StudiesRetinal DegenerationTomography, Optical CoherenceVisual Acuity

Identifiers

PMID26084958
PMCPMC4484614
OpenAlexW2263644972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.