ArticleJournal of neurophysiology2015
Hippocampus and subregions of the dorsal striatum respond differently to a behavioral strategy change on a spatial navigation task.
Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- A novel rat spatial inference task reveals rapid deduction of transitive relationships using schemas and deliberation.Behavioral neuroscience · 2026Article
- A Novel Rat Spatial Inference Task Reveals Rapid Deduction of Transitive Relationships Using Schemas and Deliberation.bioRxiv : the preprint server for biology · 2025Article
- Environmental complexity modulates information processing and the balance between decision-making systems.Neuron · 2024Article
- Article
- Article
- An Improved Dyna-Q Algorithm Inspired by the Forward Prediction Mechanism in the Rat Brain for Mobile Robot Path Planning.Biomimetics (Basel, Switzerland) · 2024Article
- Making and breaking habits: Revisiting the definitions and behavioral factors that influence habits in animals.Journal of the experimental analysis of behavior · 2024Review
- Lack of action monitoring as a prerequisite for habitual and chunked behavior: Behavioral and neural correlates.iScience · 2023Article
- Review
- Etiopathogenic Models of Psychosis Spectrum Illnesses Must Resolve Four Key Features.Biological psychiatry · 2022Review
- Computational validity: using computation to translate behaviours across species.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Dorsolateral Striatal Task-initiation Bursts Represent Past Experiences More than Future Action Plans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Melamine disrupts spatial reversal learning and learning strategy via inhibiting hippocampal BDNF-mediated neural activity.PloS one · 2021Article
- What Behavioral Abilities Emerged at Key Milestones in Human Brain Evolution? 13 Hypotheses on the 600-Million-Year Phylogenetic History of Human Intelligence.Frontiers in psychology · 2021Article
- Potential roles of the rodent medial prefrontal cortex in conflict resolution between multiple decision-making systems.International review of neurobiology · 2021Review
- Proceedings of the 2019 annual meeting of the Fetal Alcohol Spectrum Disorders Study Group.Alcohol (Fayetteville, N.Y.) · 2020Article
- Aging is not equal across memory systems.Neurobiology of learning and memory · 2020Article
- Neural substrates of habit.Journal of neuroscience research · 2020Review
- Dorsomedial prefrontal cortex and hippocampus represent strategic context even while simultaneously changing representation throughout a task session.Neurobiology of learning and memory · 2020Article
- Distinct recruitment of dorsomedial and dorsolateral striatum erodes with extended training.eLife · 2019Article
Corrections and comments
- Erratum issuedCORRIGENDUM.2020
- Erratum issuedCORRIGENDUM.2020
Authors and funding
3 authors.
Funding
Abstract
Goal-directed and habit-based behaviors are driven by multiple but dissociable decision making systems involving several different brain areas, including the hippocampus and dorsal striatum. On repetitive tasks, behavior transitions from goal directed to habit based with experience. Hippocampus has been implicated in initial learning and dorsal striatum in automating behavior, but recent studies suggest that subregions within the dorsal striatum have distinct roles in mediating habit-based and goal-directed behavior. We compared neural activity in the CA1 region of hippocampus with anterior dorsolateral and posterior dorsomedial striatum in rats on a spatial choice task, in which subjects experienced reward delivery changes that forced them to adjust their behavioral strategy. Our results confirm the importance of the hippocampus in evaluating predictive steps during goal-directed behavior, while separate circuits in the basal ganglia integrated relevant information during automation of actions and recognized when new behaviors were needed to continue obtaining rewards.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.