ArticleCritical care (London, England)2015
Arterial blood pressure targets in septic shock: is it time to move to an individualized approach?
Article in Critical care (London, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Optimal target blood pressure in critically ill adult patients with vasodilatory shock: A systematic review and meta-analysis.Frontiers in physiology · 2022Pooled it
- Exploring the optimal range of blood pressure in elderly sepsis patients: a retrospective cohort study based on MIMIC-IV data.BMC infectious diseases · 2025Article
- Optimizing Mean Arterial Pressure Targets for Septic Shock Patients With Chronic Hypertension: A Narrative Review.Health science reports · 2025Article
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- The future of intraoperative blood pressure management.Journal of clinical monitoring and computing · 2018Article
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3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Xu and colleagues evaluated the impact of increasing mean arterial blood pressure levels through norepinephrine administration on systemic hemodynamics, tissue perfusion, and sublingual microcirculation of septic shock patients with chronic hypertension. The authors concluded that, although increasing arterial blood pressure improved sublingual microcirculation parameters, no concomitant improvement in systemic tissue perfusion indicators was found. Here, we discuss why resuscitation targets may need to be individualized, taking into account the patient's baseline condition, and present directions for future research in this field.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.