Trial reportTropical medicine & international health : TM & IH2015
Stunting is associated with poor outcomes in childhood pneumonia.
Trial report in Tropical medicine & international health : TM & IH, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- What are the risk factors for death among children with pneumonia in low- and middle-income countries? A systematic review.Journal of global health · 2023Pooled it
- Slow progress towards pneumonia control for children in low-and-middle income countries as measured by pneumonia indicators: A systematic review of the literature.Journal of global health · 2022Pooled it
- Factors associated with community acquired severe pneumonia among under five children in Dhaka, Bangladesh: A case control analysis.PloS one · 2022Trial
- Prognosis of clinical pneumonia in undernourished children in rural Gambia.Pneumonia (Nathan Qld.) · 2026Article
- Multilevel modeling and mediation analysis of acute respiratory infections among under five children in Bangladesh: evidence from multiple indicator cluster survey.BMC public health · 2026Article
- District-level ecological analysis of the association between stunting and infectious diseases among children under 2 years in Rwanda, 2020-2024.Frontiers in public health · 2026Article
- Recovery Rate of Children From Pneumonia and Its Predictors in Ethiopia: A Systematic Review and Meta-Analysis.Health science reports · 2025Review
- Article
- Height status matters for risk of mortality in critically ill children.Journal of intensive care · 2024Article
- Respiratory rates among rural Gambian children: a community-based cohort study.Scientific reports · 2024Article
- Time to recovery and its predictors among under-five children admitted with severe pneumonia in East Wallaga Zone public hospitals, western Ethiopia, 2023; a retrospective cohort study.BMC pediatrics · 2024Article
- The Impact of Malnutrition on the Developing Lung and Long-Term Lung Health: A Narrative Review of Global Literature.Pulmonary therapy · 2024Review
- Article
- The effect ofHealth policy OPEN · 2021Article
- Birth size and early pneumonia predict linear growth among HIV-exposed uninfected infants.Maternal & child nutrition · 2019Article
- Pneumonia in HIV-exposed and Infected Children and Association With Malnutrition.The Pediatric infectious disease journal · 2018Article
- Risk factors associated with nasopharyngeal carriage and density ofPneumonia (Nathan Qld.) · 2018Article
- Effect of pregnancy intention, postnatal depressive symptoms and social support on early childhood stunting: findings from India.BMC pregnancy and childbirth · 2016Article
- Assessing Comorbidity of Diarrhea and Acute Respiratory Infections in Children Under 5 Years: Evidence From Kenya's Demographic Health Survey 2014.Journal of primary care & community healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 10 institutions in 7 countries.
Funding
Abstract
objectiveStunting affects 26.7% of children worldwide, and little is known about its effects on the outcomes of childhood pneumonia. We evaluated the effect of stunting on the outcomes of pneumonia among children enrolled in two large clinical trials.
methodsWe analysed data from two WHO and USAID-sponsored inpatient treatment trials, the Severe Pneumonia Evaluation Antimicrobial Research study (n = 958) and the Amoxicillin Penicillin Pneumonia International Study (n = 1702), which enrolled children aged 2-59 months across 16 sites in LMICs. We assessed the effect of stunting (height-for-age Z score < -2) on treatment outcome and time to resolution of hypoxaemic pneumonia.
resultsAmong 2542 (96%) children with valid data for height, 28% were stunted and 12.8% failed treatment by 5 days. The failure rate among stunted patients was 16.0% vs. 11.5% among non-stunted patients [unadjusted RR = 1.24 (95% CI 1.08, 1.41); adjusted RR = 1.28 (95% CI 1.10, 1.48)]. An inverse relationship was observed between height and failure rates, even among non-stunted children. Among 845 patients with hypoxaemic pneumonia, stunting was associated with a lower probability of normalisation of respiratory rate [HR = 0.63 (95% CI 0.52, 0.75)] and oxygen saturation [HR = 0.74 (95% CI 0.61, 0.89)].
conclusionsStunting increases the risk of treatment failure and is associated with a longer course of recovery in children with pneumonia. Strategies to decrease stunting may decrease the burden of adverse outcomes in childhood pneumonia in low-resource settings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.