ArticlePloS one2015
Sleep Quality of Patients with Differentiated Thyroid Cancer.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Yeur-Hur Lai, PhD, RN, School of Nursing, College of Medicine, National Taiwan University
Impacts and Testing of the "Multi-domains Active-living Program (MAP)" in Newly Diagnosed Operable Non-Muscle Invasive Bladder Cancer Patients - Current Status and the Effects of Combining With eHealth-Enhanced Randomized Controlled Trial
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Proposal for Managing Cancer-Related Insomnia: A Systematic Literature Review of Associated Factors and a Narrative Review of Treatment.Cancer medicine · 2024Pooled it
- Development and validation of a prediction model for psychological distress in patients with differentiated thyroid cancer undergoing ¹³¹I therapy.Frontiers in endocrinology · 2026Article
- Development and validation of a predictive nomogram for high-risk thyroid nodules: a retrospective analysis of sedentary time, insomnia, and elevated weight.Frontiers in oncology · 2026Article
- The relationship between sleep disturbances, depression and anxiety in differentiated thyroid cancer patients during radioiodine (131I) therapy: a longitudinal observational study.Frontiers in endocrinology · 2026Observational
- Longitudinal relationships of malnutrition risk, sleep disturbance, and fear of cancer recurrence in thyroid cancer patients: a cross-lagged panel model.Frontiers in nutrition · 2026Article
- Factors Associated with Sleep Disruption and Fatigue in Thyroid Cancer Survivors.Current oncology (Toronto, Ont.) · 2025Article
- Sleep disorders in patients with differentiated thyroid cancer: a case-control study.Endocrine · 2025Article
- The challenges experienced by patients in the early period after thyroidectomy and the effects on sleep quality.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Sleep quality during preparation for RAI: recombinant TSH vs. levothyroxine withdrawal.Frontiers in endocrinology · 2025Article
- Causal relationship between insomnia and thyroid disease: A bidirectional Mendelian randomization study.Brain and behavior · 2024Article
- Role of social support in the relationship between resilience and sleep quality among cancer patients.Frontiers in psychiatry · 2024Article
- The Relationship Between Thyroid Dysfunction and Sleep Quality Among Population of Saudi Arabia.International journal of general medicine · 2024Article
- Sleep quality of patients with papillary thyroid carcinoma: a prospective longitudinal study with 5-year follow-up.Scientific reports · 2022Article
- Sleep quality, stress and thyroid cancer: a case-control study.Journal of endocrinological investigation · 2022Article
- Article
- Impact of sleep disorders in cognitive function of thyroid cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Effects of first radioiodine ablation on functions of salivary glands in patients with differentiated thyroid cancer.Medicine · 2017Observational
- Multifocal oral melanoacanthoma associated with Addison's disease and hyperthyroidism: a case report.Archives of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to measure prevalence of sleep disturbance in patients with differentiated thyroid cancer (DTC) by calculating Pittsburgh Sleep Quality Index (PSQI), and compare these data with patients with benign thyroid nodules or normal participants.
methodsThree groups of patients participated in this cross-sectional study. In the first group, 162 patients with DTC received total thyroidectomy, and then 131I therapy. The second group consisted of 84 patients with benign thyroid nodules, who received partial thyroidectomy. The third group was 78 normal healthy control cases. PSQI was used to assess the sleep quality. Inter-group differences were analyzed by Kruskal-Wallis test or independent samples T test. χ2 test was also used to check prevalence differences of poor sleep quality among the groups. Differences of PSQI score and poor sleep quality prevalence before and after 131I therapy in the same group of DTC participants were analyzed by paired T test and Mcnemar's test.
resultsHigher PSQI score (7.59 ± 4.21) and higher rate of poor sleep quality (54.32%) were shown in DTC patients than in any other group. After 131I therapy, PSQI score and prevalence of poor sleep quality in DTC patients increased significantly to 8.78 ± 4.72 and 70.99%. Then DTC patients were divided into two subgroups based on their metastatic status. DTC patients with metastasis (87/162 cases, 53.70%) had significantly higher PSQI score (10.87 ± 5.18) and higher prevalence of poor sleep quality (79.31%).
conclusionDTC patients suffer from sleep disturbance, 131I therapy and awareness of metastatic status could worsen sleep problem. Psychological fear of cancer, nuclear medicine therapy and metastasis could be one major underlying reason. Longitude and interventional studies are necessary for further investigations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.