Evidence map›Paper›PMID 26082920›Full record

ArticleFrontiers in public health2015

Short- and Long-Term Effectiveness of a Subject's Specific Novel Brain and Vestibular Rehabilitation Treatment Modality in Combat Veterans Suffering from PTSD.

Frederick Robert Carrick, Guido Pagnacco, Kate McLellan, Ross Solis, Jacob Shores, Andre Fredieu, Joel Brandon Brock, Cagan Randall, Cameron Wright, Elena Oggero

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02003352 (Evaluation of the Effectiveness of a Novel Brain and Vestibular Rehabilitation Treatment Modality in PTSD Patients Who Have Suffered Combat Related Traumatic Brain Injuries), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02003352 nacompletednot on this map

Evaluation of the Effectiveness of a Novel Brain and Vestibular Rehabilitation Treatment Modality in PTSD Patients Who Have Suffered Combat Related Traumatic Brain Injuries

TypeinterventionalSponsorCarrick Institute for Graduate StudiesRan2014 to 2014Enrolled98ConditionsPTSD, TBIArmsFunctional Neurological Rehabilitation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Frederick Robert CarrickCarrick Institute , Cape Canaveral, FL , USA ; Global Clinical Scholars Research Training Program, Harvard Medical School , Boston, MA , USA ; Neurology, Carrick Brain Center , Dallas, TX , USA.
Guido PagnaccoCarrick Institute , Cape Canaveral, FL , USA ; Electrical and Computer Engineering, University of Wyoming , Laramie, WY , USA.
Kate McLellanCarrick Institute , Cape Canaveral, FL , USA ; Neurology, Carrick Brain Center , Dallas, TX , USA.
Ross SolisNeurology, Carrick Brain Center , Dallas, TX , USA.
Jacob ShoresNeurology, Carrick Brain Center , Dallas, TX , USA.
Andre FredieuNeurology, Carrick Brain Center , Dallas, TX , USA.
Joel Brandon BrockNeurology, Carrick Brain Center , Dallas, TX , USA.
Cagan RandallNeurology, Carrick Brain Center , Dallas, TX , USA.
Cameron WrightCarrick Institute , Cape Canaveral, FL , USA ; Electrical and Computer Engineering, University of Wyoming , Laramie, WY , USA.
Elena OggeroCarrick Institute , Cape Canaveral, FL , USA ; Electrical and Computer Engineering, University of Wyoming , Laramie, WY , USA.
Carrick Institute · USUniversity of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTreatment for post-traumatic stress disorder (PTSD) in combat veterans that have a long-term positive clinical effect has the potential to modify the treatment of PTSD. This outcome may result in changed and saved lives of our service personnel and their families. In a previous before-after-intervention study, we demonstrated high statistical and substantively significant short-term changes in the Clinician Administered DSM-IV PTSD Scale (CAPS) scores after a 2-week trial of a subject's particular novel brain and vestibular rehabilitation (VR) program. The long-term maintenance of PTSD severity reduction was the subject of this study. MATERIAL AND

methodsWe studied the short- and long-term effectiveness of a subject's particular novel brain and VR treatment of PTSD in subjects who had suffered combat-related traumatic brain injuries in terms of PTSD symptom reduction. The trial was registered as ClinicalTrials.gov Identifier: NCT02003352. We analyzed the difference in the CAPS scores pre- and post-treatment (1 week and 3 months) using our subjects as their matched controls.

resultsThe generalized least squares (GLS) technique demonstrated that with our 26 subjects in the 3 timed groups the R (2) within groups was 0.000, R (2) between groups was 0.000, and overall the R (2) was 0.000. The GLS regression was strongly statistically significant z = 21.29, p < 0.001, 95% CI [58.7, 70.63]. The linear predictive margins over time demonstrated strong statistical and substantive significance of decreasing PTSD severity scores for all timed CAPS tests. DISCUSSION: Our investigation has the promise of the development of superior outcomes of treatments in this area that will benefit a global society. The length of the treatment intervention involved (2 weeks) is less that other currently available treatments and has profound implications for cost, duration of disability, and outcomes in the treatment of PTSD in combat veterans.

Indexed as

brain rehabilitationDSM-IV CAPSoff vertical axis rotationPTSDvestibular rehabilitation

Identifiers

PMID26082920
PMCPMC4450724
OpenAlexW2167666696

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.