ArticleFrontiers in human neuroscience2015
A Cohort Pilot Study on HIV-Associated Neuropsychological Impairments in Hemophilia Patients.
Article in Frontiers in human neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Training Cognitive Functions Using Mobile Apps in Breast Cancer Patients: Systematic Review.JMIR mHealth and uHealth · 2019Pooled it
- Neurocognitive dysfunction and brain FDG-PET/CT findings in HIV-infected hemophilia patients and HIV-infected non-hemophilia patients.PloS one · 2020Article
- MicroRNAs and the Genetic Nexus of Brain Aging, Neuroinflammation, Neurodegeneration, and Brain Trauma.Aging and disease · 2019Review
- A systematic literature review exploring the prevalence of post-traumatic stress disorder and the role played by stress and traumatic stress in breast cancer diagnosis and trajectory.Breast cancer (Dove Medical Press) · 2017Review
- Value as the key concept in the health care system: how it has influenced medical practice and clinical decision-making processes.Journal of multidisciplinary healthcare · 2017Article
- Medical decision making and risky choices: psychological and medicolegal consequences of HIV and HCV contamination of blood products.HIV/AIDS (Auckland, N.Z.) · 2017Article
- The Role of Frontal-Subcortical Circuitry in Neuropsychological Deficit of Attention: Hypothesis and Results in Two Coagulation Disorders.Frontiers in human neuroscience · 2016Article
- Decisions and the involvement of cancer patient survivors: a moral imperative.Journal of healthcare leadership · 2016Article
- Distress and Psychosocial Needs in Patients Accessing a Cancer Day Surgery Division: Implications for Clinical Decision Making.Frontiers in psychology · 2016Article
- Value-Based Model: A New Perspective in Medical Decision-making.Frontiers in public health · 2016Article
- What are judgment skills in health literacy? A psycho-cognitive perspective of judgment and decision-making research.Patient preference and adherence · 2015Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite advances in the management of HIV infection with the introduction of combination antiretroviral therapy, it is well known that HIV can directly infect the central nervous system and, as a result of such infection, neuropsychological impairments can be manifested. In this study, we tried to determine whether seropositivity was associated with a poor neuropsychological performance in patients with hemophilia and HIV. Such a cohort of patients is very often underrepresented and understudied in the HIV literature. To amend such a gap, we carried out an extensive neuropsychological evaluation on these patients, and compared their performance with that of a group of seronegative hemophilia patients. The results revealed that HIV infection in HIV-seropositive (HIV+) hemophilia patients was associated with deficits in attention, short-term memory, abstraction, and visual recognition. Such results are still preliminary and explorative due to the small cohort of patients enrolled. However, the results do seem to have some important implications for day-to-day functioning, as the level of impairment detected may cause difficulties in completing common everyday tasks such as maintaining adherence to complex medication regimens or maintaining social life activities. Continued research into the mechanisms related to HIV and neurocognitive dysfunction may provide targets for interventions that could have meaningful consequences in the real world for HIV hemophilia patients.
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