Evidence map›Paper›PMID 26082400›Full record

ArticlePlant physiology2015

Selection for Improved Energy Use Efficiency and Drought Tolerance in Canola Results in Distinct Transcriptome and Epigenome Changes.

Aurine Verkest, Marina Byzova, Cindy Martens, Patrick Willems, Tom Verwulgen, Bram Slabbinck, Debbie Rombaut, Jan Van de Velde, Klaas Vandepoele, Evi Standaert and 4 more

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Article in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it

0cells of the map it votes in

23citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

Heterochromatin reorganization associated with the transcriptional reprogramming under viral infection in Arabidopsis.Nucleic acids research · 2026
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Studying DNA Methylation for Transgenerational Inheritance.Methods in molecular biology (Clifton, N.J.) · 2026
Article
The Epigenetic Regulation of Agronomic Traits and Environmental Adaptability in Brassicas.Plant, cell & environment · 2025
Review
The nicotinamide hypothesis revisited-plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione.FEBS letters · 2025
Review
Epigenetic odyssey to decrypt the hidden code for sustainable brassica production: enhancing yield, stress resilience and nutritional quality.Frontiers in plant science · 2025
Review
Mechanisms of Plant Epigenetic Regulation in Response to Plant Stress: Recent Discoveries and Implications.Plants (Basel, Switzerland) · 2024
Review
Changes in epigenetic features in legumes under abiotic stresses.The plant genome · 2023
Review
Regulation of DNA damage response by trimeric G-proteins.iScience · 2023
Article
Transcriptional Stress Memory and Transgenerational Inheritance of Drought Tolerance in Plants.International journal of molecular sciences · 2022
Review
Recent Advances for Drought Stress Tolerance in Maize (Frontiers in plant science · 2022
Review
Epigenetic regulation of salinity stress responses in cereals.Molecular biology reports · 2022
Review
Exploration of Epigenetics for Improvement of Drought and Other Stress Resistance in Crops: A Review.Plants (Basel, Switzerland) · 2021
Review
PhosPhAt 4.0: An Updated Arabidopsis Database for Searching Phosphorylation Sites and Kinase-Target Interactions.Methods in molecular biology (Clifton, N.J.) · 2021
Article
Transcriptional Regulation of Protein Phosphatase 2C Genes to Modulate Abscisic Acid Signaling.International journal of molecular sciences · 2020
Review
Recurrent Drought Conditions Enhance the Induction of Drought Stress Memory Genes inFrontiers in genetics · 2020
Article
Physiological and Transcriptional Responses of Industrial Rapeseed (International journal of molecular sciences · 2019
Article
Plant-RRBS, a bisulfite and next-generation sequencing-based methylome profiling method enriching for coverage of cytosine positions.BMC plant biology · 2017
Article
Genome-Wide Identification and Characterization of SPX Domain-Containing Members and Their Responses to Phosphate Deficiency inFrontiers in plant science · 2017
Article
Chromatin and epigenetics in all their states: Meeting report of the first conference on Epigenetic and Chromatin Regulation of Plant Traits - January 14 - 15, 2016 - Strasbourg, France.Epigenetics · 2016
Article
Genome-wide identification and homeolog-specific expression analysis of the SnRK2 genes in Brassica napus guard cells.Plant molecular biology · 2016
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Aurine VerkestDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).ORCID http://orcid.org/0000-0003-3683-8537

Marina ByzovaDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).ORCID http://orcid.org/0000-0001-8445-9377

Cindy MartensDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Patrick WillemsDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).ORCID http://orcid.org/0000-0003-4667-2294

Tom VerwulgenDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Bram SlabbinckDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Debbie RombautDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Jan Van de VeldeDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Klaas VandepoeleDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).ORCID http://orcid.org/0000-0003-4790-2725

Evi StandaertDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Marrit PeetersDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).

Mieke Van LijsebettensDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.).ORCID http://orcid.org/0000-0002-7632-1463

Frank Van BreusegemDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.) frank.vanbreusegem@psb.vib-ugent.be marc.deblock@bayer.com.ORCID http://orcid.org/0000-0002-3147-0860

Marc De BlockDepartment of Plant Systems Biology, VIB, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium (A.V., M.B., C.M., P.W., T.V., B.S., D.R., J.V.d.V., K.V., M.V.L., F.V.B.);Bayer CropScience, 9052 Ghent, Belgium (C.M., E.S., M.P., M.D.B.);Department of Medical Protein Research, VIB, 9000 Ghent, Belgium (P.W.); andDepartment of Biochemistry, Ghent University, 9000 Ghent, Belgium (P.W.) frank.vanbreusegem@psb.vib-ugent.be marc.deblock@bayer.com.ORCID http://orcid.org/0000-0003-0206-3825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To increase both the yield potential and stability of crops, integrated breeding strategies are used that have mostly a direct genetic basis, but the utility of epigenetics to improve complex traits is unclear. A better understanding of the status of the epigenome and its contribution to agronomic performance would help in developing approaches to incorporate the epigenetic component of complex traits into breeding programs. Starting from isogenic canola (Brassica napus) lines, epilines were generated by selecting, repeatedly for three generations, for increased energy use efficiency and drought tolerance. These epilines had an enhanced energy use efficiency, drought tolerance, and nitrogen use efficiency. Transcriptome analysis of the epilines and a line selected for its energy use efficiency solely revealed common differentially expressed genes related to the onset of stress tolerance-regulating signaling events. Genes related to responses to salt, osmotic, abscisic acid, and drought treatments were specifically differentially expressed in the drought-tolerant epilines. The status of the epigenome, scored as differential trimethylation of lysine-4 of histone 3, further supported the phenotype by targeting drought-responsive genes and facilitating the transcription of the differentially expressed genes. From these results, we conclude that the canola epigenome can be shaped by selection to increase energy use efficiency and stress tolerance. Hence, these findings warrant the further development of strategies to incorporate epigenetics into breeding.

Indexed as

Epigenesis, GeneticTranscriptomeAbscisic AcidBrassica napusBreedingCrops, AgriculturalDroughtsEnergy MetabolismEpigenomicsGene Expression ProfilingGene Expression Regulation, PlantOsmosisPhenotypePlant Growth RegulatorsSequence Analysis, RNAStress, PhysiologicalAbscisic AcidPlant Growth Regulators

Identifiers

PMID26082400

DOI10.1104/pp.15.00155

PMCPMC4528734

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