Evidence map›Paper›PMID 26082346›Full record

ArticleLab on a chip2015

An acoustofluidic sputum liquefier.

Po-Hsun Huang, Liqiang Ren, Nitesh Nama, Sixing Li, Peng Li, Xianglan Yao, Rosemarie A Cuento, Cheng-Hsin Wei, Yuchao Chen, Yuliang Xie and 6 more

Abstract read
In one paragraph

Article in Lab on a chip, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. [High stability enhanced ultrasonic microfluidic structure with flexible tip coupled bubbles].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Acoustic Microfluidics.Annual review of analytical chemistry (Palo Alto, Calif.) · 2020
    Review
  8. Article
  9. Acoustofluidic Synthesis of Particulate Nanomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Article
  10. Acoustofluidic methods in cell analysis.Trends in analytical chemistry : TRAC · 2019
    Article
  11. Open source acoustofluidics.Lab on a chip · 2019
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Po-Hsun HuangDepartment of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA. junhuang@psu.edu.
Liqiang Ren
Nitesh Nama
Sixing Li
Peng Li
Xianglan Yao
Rosemarie A Cuento
Cheng-Hsin Wei
Yuchao Chen
Yuliang Xie
Ahmad Ahsan Nawaz
Yael G Alevy
Michael J Holtzman
J Philip McCoy
Stewart J Levine
Tony Jun Huang

Funding

Flow Cytometry Core FacilityZICHL005905 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI DAGUR, PRADEEP · 2009 to 2025
$32.3M
Fiberoptic Bronchoscopy in Patients with AsthmaZIAHL006197 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEVINE, STEWART · 2015 to 2024
$14.8M
Intramural NIH HHS ZIC HL005905
6 · The paper itself

Abstract

We demonstrate the first microfluidic-based on-chip liquefaction device for human sputum samples. Our device is based on an acoustofluidic micromixer using oscillating sharp edges. This acoustofluidic sputum liquefier can effectively and uniformly liquefy sputum samples at a throughput of 30 μL min(-1). Cell viability and integrity are maintained during the sputum liquefaction process. Our acoustofluidic sputum liquefier can be conveniently integrated with other microfluidic units to enable automated on-chip sputum processing and analysis.

Indexed as

Cell SurvivalEosinophilsEquipment DesignFlow CytometryHumansMicrofluidic Analytical TechniquesNeutrophilsSonicationSpecimen HandlingSputum

Identifiers

PMID26082346
PMCPMC6518399

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.