ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2015
A single base substitution in BADH/AMADH is responsible for fragrance in cucumber (Cucumis sativus L.), and development of SNAP markers for the fragrance.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- EasyKASP: a simple and fast tool for KASP primer design.BMC bioinformatics · 2025Article
- A mutation in CmoBADH results in the production of 2-acetyl-1-pyrroline, conferring a 'taro-like' aroma in Cucurbita moschata.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Genome editing in maize and sorghum: A comprehensive review of CRISPR/Cas9 and emerging technologies.The plant genome · 2025Review
- The development of ideal insertion and deletion (InDel) markers and initial indel map variation in cucumber using re-sequenced data.BMC genomics · 2025Article
- Article
- Genetic mapping and validation of QTL controlling fruit diameter in cucumber.BMC plant biology · 2024Article
- A non-synonymous SNP in homolog ofGenetic resources and crop evolution · 2023Article
- Assessment of the 'taro-like' aroma of pumpkin fruit (Food chemistry: X · 2022Article
- A Sequence Variation inInternational journal of molecular sciences · 2022Article
- A SNP of betaine aldehyde dehydrogenase (BADH) enhances an aroma (2-acetyl-1-pyrroline) in sponge gourd (Luffa cylindrica) and ridge gourd (Luffa acutangula).Scientific reports · 2022Article
- Molecular research progress and improvement approach of fruit quality traits in cucumber.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Integrated Metabolome and Transcriptome Analysis Unveils Novel Pathway Involved in the Formation of Yellow Peel in Cucumber.International journal of molecular sciences · 2021Article
- Crop Quality Improvement Through Genome Editing Strategy.Frontiers in genome editing · 2021Review
- Article
- The Formation of Fruit Quality inFrontiers in plant science · 2021Review
- Article
- Recent progress on the molecular breeding of Cucumis sativus L. in China.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Review
- Molecularly tagged genes and quantitative trait loci in cucumber with recommendations for QTL nomenclature.Horticulture research · 2020Review
- Mapping and identification of CsUp, a gene encoding an Auxilin-like protein, as a putative candidate gene for the upward-pedicel mutation (up) in cucumber.BMC plant biology · 2019Article
- Cucumber CsTRY Negatively Regulates Anthocyanin Biosynthesis and Trichome Formation When Expressed in Tobacco.Frontiers in plant science · 2019Article
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5 authors.
Funding
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Abstract
Sequence analysis revealed that an SNP (A1855G) in CsBADH of cucumber accession PK2011T202 causes amino acid change in a highly conserved motif, Y163C. Gene mapping showed association between the SNP and the fragrance. Pandan-like fragrance is a value-added trait in several food crops such as rice, vegetable soybean and sorghum. The fragrance is caused by the volatile chemical 2-acetyl-1-pyrroline (2AP). Mutation(s) in betaine aldehyde dehydrogenase 2 (BADH2; also known as aminoaldehyde dehydrogenase 2) gene causes defective BADH2 and results in biosynthesis of 2AP. Recently, cucumber cultivars possessing pandan-like fragrance were discovered in Thailand. In this study, we report an association between CsBADH and the fragrance in cucumber accession "PK2011T202". Gene expression analysis of CsBADH in leaves of PK2011T202 and "301176" (non-fragrant) at various growth stages revealed that CsBADH was expressed in both accessions. Sequence comparison of CsBADH showed that PK2011T202 possesses a single base substitution (A1855G) in exon 5 which causes an amino acid change in a highly conserved motif of BADH, Y163C. Single nucleotide-amplified polymorphism markers were developed to detect the SNP polymorphism between the wild-type and fragrance alleles. Since CsBADH is located on chromosome 1, quantitative trait locus (QTL) mapping was conducted for this chromosome using an F2 and a backcross populations developed from the cross between PK2011T202 and 301176. QTL analysis in both populations showed that the major QTL for fragrance, qFgr, was co-localized with the CsBADH. We concluded that the defect function of CsBADH is responsible for fragrance in cucumber PK2011T202.
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