Evidence map›Paper›PMID 26081922›Full record

ArticleJournal of veterinary internal medicine

Effect of Feeding an Iodine-Restricted Diet in Cats with Spontaneous Hyperthyroidism.

T Y Hui, D S Bruyette, G E Moore, J C Scott-Moncrieff

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. 2016 AAFP Guidelines for the Management of Feline Hyperthyroidism.Journal of feline medicine and surgery · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

T Y HuiDepartment of Veterinary Clinical Sciences, Purdue University College of Veterinary Medicine, West Lafayette, IN.
D S BruyetteVCA-West Los Angeles Animal Hospital, Los Angeles, CA.
G E MooreDepartment of Veterinary Clinical Sciences, Purdue University College of Veterinary Medicine, West Lafayette, IN.
J C Scott-MoncrieffDepartment of Veterinary Clinical Sciences, Purdue University College of Veterinary Medicine, West Lafayette, IN.
Purdue University West Lafayette · USWest Los Angeles College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExclusive feeding of an iodine-restricted diet has been proposed as a method for controlling clinical manifestations of hyperthyroidism in hyperthyroid cats.

objectivesTo determine the effect of feeding an iodine-restricted diet on TT4 concentrations and clinical signs in cats with spontaneous hyperthyroidism. ANIMALS: Forty-nine client-owned cats with spontaneous hyperthyroidism.

methodsRetrospective case series. Hyperthyroid cats were exclusively fed a commercially available iodine-restricted diet. Clinical response was assessed by change in weight and heart rate and serum TT4, blood urea nitrogen (BUN), and creatinine concentrations at various times during dietary management (21-60 days, 60-180 days).

resultsSerum TT4 normalized in 20/48 cats (42%) and 39/47 cats (83%) at 21-60 days and 61-180 days, respectively. Cats in which the TT4 concentrations were still above reference range at 21-60 days had a significantly higher starting TT4 than those that normalized their TT4 levels during the same time period (P = .038). Body weight did not significantly increase (P = .34) nor heart rate decrease (P = .64) during the study. There was a significant decrease in serum creatinine (P = .028). Cats in the low reference range for serum TT4 concentrations did not have a significant increase in body weight (P = .41) nor creatinine (P = .54) when compared to those with high reference range. CONCLUSIONS AND CLINICAL IMPORTANCE: Restricted-iodine diets were effective at maintaining serum TT4 concentrations within reference ranges for a majority of cats with spontaneous hyperthyroidism over 1 year, although not all clinical signs of hyperthyroidism improved.

Indexed as

Animal FeedAnimalsCat DiseasesCatsDietFemaleHyperthyroidismIodineMaleRetrospective StudiesThyroxineTreatment OutcomeIodineThyroxineEndocrineFelineThyroid glandThyroid hormone

Identifiers

PMID26081922
PMCPMC4895365
OpenAlexW1501851772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.