Evidence map›Paper›PMID 26081838›Full record

ArticleMalaria journal2015

Forecasting malaria in a highly endemic country using environmental and clinical predictors.

Kate Zinszer, Ruth Kigozi, Katia Charland, Grant Dorsey, Timothy F Brewer, John S Brownstein, Moses R Kamya, David L Buckeridge

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Impact of Climate Variability and Interventions on Malaria Incidence and Forecasting in Burkina Faso.International journal of environmental research and public health · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Kate ZinszerClinical and Health Informatics Group, McGill University, 1140 Pine Ave West, Montreal, QC, H3A 1A3, Canada. kate.zinszer@mail.mcgill.ca.
Ruth KigoziUganda Malaria Surveillance Project, Kampala, Uganda. kigoziruth@gmail.com.
Katia CharlandClinical and Health Informatics Group, McGill University, 1140 Pine Ave West, Montreal, QC, H3A 1A3, Canada. charlandk@yahoo.com.
Grant DorseySchool of Medicine, University of California San Francisco, San Francisco, CA, USA. gdorsey@medsfgh.ucsf.edu.
Timothy F BrewerUniversity of California Los Angeles, Los Angeles, CA, USA. tbrewer@conet.ucla.edu.
John S BrownsteinChildren's Hospital Informatics Program, Boston Children's Hospital, Boston, MA, USA. John.Brownstein@childrens.harvard.edu.
Moses R KamyaCollege of Health Sciences, Makerere University, Kampala, Uganda. mkamya@infocom.co.ug.
David L BuckeridgeClinical and Health Informatics Group, McGill University, 1140 Pine Ave West, Montreal, QC, H3A 1A3, Canada. David.Buckeridge@mcgill.ca.
McGill University · CABoston Children's Hospital · USMakerere University · UGMalaria Consortium · UGUniversity of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

Transmission ProjectU19AI089674 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MATTHEW G DORSEY · 2010 to 2026
$29.3M
NIAID NIH HHS U19 AI089674NIAID NIH HHS U19AI089674
6 · The paper itself

Abstract

backgroundMalaria thrives in poor tropical and subtropical countries where local resources are limited. Accurate disease forecasts can provide public and clinical health services with the information needed to implement targeted approaches for malaria control that make effective use of limited resources. The objective of this study was to determine the relevance of environmental and clinical predictors of malaria across different settings in Uganda.

methodsForecasting models were based on health facility data collected by the Uganda Malaria Surveillance Project and satellite-derived rainfall, temperature, and vegetation estimates from 2006 to 2013. Facility-specific forecasting models of confirmed malaria were developed using multivariate autoregressive integrated moving average models and produced weekly forecast horizons over a 52-week forecasting period.

resultsThe model with the most accurate forecasts varied by site and by forecast horizon. Clinical predictors were retained in the models with the highest predictive power for all facility sites. The average error over the 52 forecasting horizons ranged from 26 to 128% whereas the cumulative burden forecast error ranged from 2 to 22%.

conclusionsClinical data, such as drug treatment, could be used to improve the accuracy of malaria predictions in endemic settings when coupled with environmental predictors. Further exploration of malaria forecasting is necessary to improve its accuracy and value in practice, including examining other environmental and intervention predictors, including insecticide-treated nets.

Indexed as

Endemic DiseasesEnvironmentAdolescentAdultAgedChildChild, PreschoolFemaleHumansInfantMalariaMaleMiddle AgedModels, TheoreticalSeasonsUganda

Identifiers

PMID26081838
PMCPMC4470343
OpenAlexW1537316108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.