ArticleBMC research notes2015
Outcome and prognosis of hypoxic brain damage patients undergoing neurological early rehabilitation.
Article in BMC research notes, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care.Intensive care medicine · 2025Guideline
- Trial of Edaravone for severe hypoxic ischemic encephalopathy in adults: a double-blind placebo-controlled study.Journal of neurology · 2026Trial
- Diencephalic integrity explains aspects of hippocampal amnesia.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Update on hypoxic-ischemic brain injury: Prognosis and management.World journal of methodology · 2026Review
- [Aims of rehabilitation after successful resuscitation].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2026Review
- Hypoxic Brain Injury Mimicking a Spinal Cord Disease: An Unusual Neurological Consequence of Cardiac Arrest.Cureus · 2025Article
- Endothelial -targeted CD39 is protective in a mouse model of global forebrain ischaemia.Journal of neuroinflammation · 2025Article
- Etiology and Functional Outcomes following Hypoxic Ischemic Encephalopathy in Adults: A 10-Year Retrospective Cohort Study.Archives of rehabilitation research and clinical translation · 2025Article
- Parietal-specific activation reveals pain from inadequate levels of altitude acclimatization/ adaptation.PloS one · 2025Article
- Contributions of Basal Ganglia Circuits to Perception, Attention, and Consciousness.Journal of cognitive neuroscience · 2024Review
- Review
- Correlation between Thalamocortical Tract and Default Mode Network with Consciousness Levels in Hypoxic-Ischemic Brain Injury Patients: A Comparative Study Using the Coma Recovery Scale-Revised.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Review
- Factors Associated with Newly Developed Postoperative Neurological Complications in Patients with Emergency Surgery for Acute Type A Aortic Dissection.Medicina (Kaunas, Lithuania) · 2023Article
- Hemiplegia resulting from acute carbon monoxide poisoning.Diving and hyperbaric medicine · 2023Article
- Relationship between Coma Recovery Scale-Revised and the Thalamocortical Tract of Ascending Reticular Activating System in Hypoxic-Ischemic Brain Injury: A Pilot Study.Healthcare (Basel, Switzerland) · 2023Article
- Article
- Psychophysiological Effects of Biographical Interventions in People With Unresponsive Wakefulness Syndrome and Minimally Conscious State.Frontiers in neurology · 2022Article
- Post-Hypoxic Myoclonus Status following Out-of-Hospital Cardiac Arrest-Does It still Predict a Poor Outcome? A Retrospective Study.Healthcare (Basel, Switzerland) · 2021Article
- Secondary hypoxic ischemia alters neurobehavioral outcomes, neuroinflammation, and oxidative stress in mice exposed to controlled cortical impact.Clinical and experimental emergency medicine · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of patients suffering from hypoxic brain damage is increasing. Long-term outcome data and prognostic factors for either poor or good outcome are lacking.
methodsThis retrospective study included 93 patients with hypoxic brain damage undergoing neurological early rehabilitation [length of stay: 108.5 (81.9) days]. Clinical data, validated outcome scales (e.g. Barthel Index-BI, Early Rehabilitation Index-ERI, Glasgow Coma Scale-GCS, Coma Remission Scale-CRS), neuroimaging data, electroencephalography (EEG) and evoked potentials were analyzed.
results75.3% had a poor outcome (defined as BI <50). 38 (40.9%) patients were discharged to a nursing care facility, 21 (22.6%) to subsequent rehabilitation, 17 (18.3%) returned home, 9 (9.7%) needed further acute-care hospital treatment and 8 (8.6%) died. Barthel Index on admission as well as coma length were strong predictors of outcome from hypoxic brain damage. In addition, duration of vegetative instability, prolongation of wave III in visual evoked potentials (flash VEP), theta and delta rhythm in EEG, ERI, GCS and CRS on admission were related to poor outcome. All patients with bilateral hypodensities of the basal ganglia belonged to the poor outcome group. Age had no independent influence on functional status at discharge.
conclusionsAs with other studies on neurological rehabilitation, functional status on admission turned out to be a strong predictor of outcome from hypoxic brain damage.
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