SynthesisEuropean journal of clinical nutrition2016
Coffee consumption and the risk of lung cancer: an updated meta-analysis of epidemiological studies.
Synthesis in European journal of clinical nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- A systematic review and dose-response meta-analysis of prospective cohort studies on coffee consumption and risk of lung cancer.Scientific reports · 2024Pooled it
- Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes.BMJ (Clinical research ed.) · 2017Pooled it
- Coffee consumption and risk of all-cause, cardiovascular, and cancer mortality in smokers and non-smokers: a dose-response meta-analysis.European journal of epidemiology · 2016Pooled it
- Higher Caffeinated Coffee Intake Is Associated with Reduced Malignant Melanoma Risk: A Meta-Analysis Study.PloS one · 2016Pooled it
- Antioxidants in Oxidative Stress and Obesity-Associated Diseases: Molecular Mechanisms and Potential Health Implications.Biomedicines · 2026Review
- Dietary pattern and odds of lung cancer: a large case-control study in Iran.BMC nutrition · 2025Article
- Coffee consumption, cancer, and healthy aging: epidemiological evidence and underlying mechanisms.GeroScience · 2025Review
- Vitamin K Intake and Risk of Lung Cancer: The Japan Collaborative Cohort Study.Journal of epidemiology · 2023Article
- Dietary Heat-Treatment Contaminants Exposure and Cancer: A Case Study from Turkey.Foods (Basel, Switzerland) · 2023Article
- Causal relationship from coffee consumption to diseases and mortality: a review of observational and Mendelian randomization studies including cardiometabolic diseases, cancer, gallstones and other diseases.European journal of nutrition · 2022Review
- A Decade of Research on Coffee as an Anticarcinogenic Beverage.Oxidative medicine and cellular longevity · 2021Review
- The investigation of the healing effect of active ingredients in traditional medicinal plants on lung cancer.Medical oncology (Northwood, London, England) · 2020Article
- Article
- Associations between tea and coffee beverage consumption and the risk of lung cancer in the Singaporean Chinese population.European journal of nutrition · 2020Article
- Coffee Consumption and Lung Cancer Risk: A Prospective Cohort Study in Khon Kaen Thailand.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Dietary Research on Coffee: Improving Adjustment for Confounding.Current developments in nutrition · 2020Review
- Coffee Consumption and Lung Cancer Risk: The Japan Public Health Center-Based Prospective Study.Journal of epidemiology · 2018Article
- Designing Dietary Recommendations Using System Level Interactomics Analysis and Network-Based Inference.Frontiers in physiology · 2017Article
- Coffee and cancer risk: A meta-analysis of prospective observational studies.Scientific reports · 2016Article
- Coffee consumption and the risk of cancer in the Norwegian Women and Cancer (NOWAC) Study.European journal of epidemiology · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesCoffee is one of the most popularly consumed beverages worldwide. Many epidemiological studies have investigated the association between coffee consumption and lung cancer risk, but the results are inconsistent. Hence, we conducted a systematic analysis of relevant population-based studies to examine this association and derive a more precise estimation. SUBJECTS/
methodsThe Cochrane library, PubMed and Embase databases were searched to identify studies published through Mar 2015 that met the predetermined inclusion criterion. Seventeen studies (5 cohort and 12 case-control studies) involving 12 276 cases and 102 516 controls were included.
resultsThe summary odds ratio (OR) of lung cancer was 1.17 (95% confidence interval (CI): 1.03-1.33) for coffee drinkers compared with nondrinkers and 1.31 (95% CI: 1.11-1.55) for the highest category of coffee consumption compared with the lowest category. Compared with nondrinkers, the pooled ORs for lung cancer were 1.10 (95% CI: 0.92-1.31) for ⩽1 cup per day, 1.10 (95% CI: 0.93-1.30) for 2-3 cups per day and 1.20 (95% CI: 1.02-1.39) for ⩾3 cups per day. Further analysis showed that the ORs for hospital-based case-control studies, population-based case-control studies and prospective cohort studies were 1.36 (95% CI: 1.10-1.69), 0.99 (95% CI: 0.77-1.28) and 1.59 (95% CI: 1.26-2.00), respectively. Significant associations for high coffee intake with increased risk of lung cancer were observed in men (OR=1.41 95% CI: 1.21-1.63), but not in women (OR=1.16, 95% CI: 0.86-1.56), in American (OR=1.34 95% CI: 1.08-1.65) and Asian populations (OR=1.49 95% CI: 1.28-1.74), but not in European populations (OR=1.12, 95% CI: 0.74-1.67), and in smokers (OR=1.24, 95% CI: 1.00-1.54), but not in nonsmokers (OR=0.85, 95% CI: 0.64-1.11). Particularly over the last 5 years, studies have consistently indicated that lung cancer risk is significantly increased by 47% in the population with the highest category intake of coffee compared with that with the lowest category intake (OR=1.47, 95% CI: 1.21-1.79).
conclusionThe present study suggested that coffee intake was associated with an increased risk of lung cancer.
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