ArticleScientific reports2015
Profiling molecular and behavioral circadian rhythms in the non-symbiotic sea anemone Nematostella vectensis.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Stable yet shifting: Early toxin dynamics in typical and atypical clownfish-anemone symbioses.Toxicon: X · 2026Article
- DNA damage modulates sleep drive in basal cnidarians with divergent chronotypes.Nature communications · 2026Article
- A light-entrained clock mechanism in a hydrozoan jellyfish synchronizes evening gamete release.PLoS biology · 2026Article
- Sleeping upside-down: Knockdown of a sleep-associated gene induces daytime sleep in the jellyfishProceedings of the National Academy of Sciences of the United States of America · 2025Article
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- Temporal gene expression patterns in the coralScience advances · 2022Article
- Two light sensors decode moonlight versus sunlight to adjust a plastic circadian/circalunidian clock to moon phase.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Urbanization comprehensively impairs biological rhythms in coral holobionts.Global change biology · 2022Article
- Cellular pathways during spawning induction in the starlet sea anemone Nematostella vectensis.Scientific reports · 2021Article
- Photoreceptor Diversification Accompanies the Evolution of Anthozoa.Molecular biology and evolution · 2021Article
- Evidence of learning and memory in the juvenile dwarf cuttlefish Sepia bandensis.Learning & behavior · 2020Article
- Intrinsic disorder is an essential characteristic of components in the conserved circadian circuit.Cell communication and signaling : CCS · 2020Review
- Decoupling behavioral and transcriptional responses to color in an eyeless cnidarian.BMC genomics · 2020Article
- Article
- Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch.eLife · 2020Article
- Demystifying Circalunar and Diel Rhythmicity in Acropora digitifera under Constant Dim Light.iScience · 2019Article
- Chromatin dynamics enable transcriptional rhythms in the cnidarian Nematostella vectensis.PLoS genetics · 2019Article
- Diel patterning in the bacterial community associated with the sea anemoneEcology and evolution · 2019Article
- Dynamic remodeling of the interactomes of Nematostella vectensis Hsp70 isoforms under heat shock.Journal of proteomics · 2019Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endogenous circadian clocks are poorly understood within early-diverging animal lineages. We have characterized circadian behavioral patterns and identified potential components of the circadian clock in the starlet sea anemone, Nematostella vectensis: a model cnidarian which lacks algal symbionts. Using automatic video tracking we showed that Nematostella exhibits rhythmic circadian locomotor activity, which is persistent in constant dark, shifted or disrupted by external dark/light cues and maintained the same rate at two different temperatures. This activity was inhibited by a casein kinase 1δ/ε inhibitor, suggesting a role for CK1 homologue(s) in Nematostella clock. Using high-throughput sequencing we profiled Nematostella transcriptomes over 48 hours under a light-dark cycle. We identified 180 Nematostella diurnally-oscillated transcripts and compared them with previously established databases of adult and larvae of the symbiotic coral Acropora millepora, revealing both shared homologues and unique rhythmic genes. Taken together, this study further establishes Nematostella as a non-symbiotic model organism to study circadian rhythms and increases our understanding about the fundamental elements of circadian regulation and their evolution within the Metazoa.
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