Evidence map›Paper›PMID 26080688›Full record

ArticleAIDS and behavior2015

Periconception HIV Risk Behavior Among Men and Women Reporting HIV-Serodiscordant Partners in KwaZulu-Natal, South Africa.

L T Matthews, J A Smit, L Moore, C Milford, R Greener, F N Mosery, H Ribaudo, K Bennett, T L Crankshaw, A Kaida and 3 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

L T MatthewsDivision of Infectious Disease and Center for Global Health, Massachusetts General Hospital, 100 Cambridge Street, 15th Floor, Boston, MA, 02114, USA. ltmatthews@partners.org.
J A SmitMatCH Research [Maternal, Adolescent and Child Health Research], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa.
L MooreMatCH Research [Maternal, Adolescent and Child Health Research], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa.
C MilfordMatCH Research [Maternal, Adolescent and Child Health Research], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa.
R GreenerMatCH Research [Maternal, Adolescent and Child Health Research], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa.
F N MoseryMatCH Research [Maternal, Adolescent and Child Health Research], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa.
H RibaudoCenter for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA, USA.
K BennettBennett Statistical Consulting, Inc., Ballston Lake, NY, USA.
T L CrankshawHealth Economics and HIV and AIDS Research Division (HEARD), University of KwaZulu-Natal, Durban, South Africa.
A KaidaFaculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada.
C PsarosBehavioral Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
S A SafrenBehavioral Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
D R BangsbergDivision of Infectious Disease and Center for Global Health, Massachusetts General Hospital, 100 Cambridge Street, 15th Floor, Boston, MA, 02114, USA.
University of the Witwatersrand · ZAHarvard University · USMassachusetts General Hospital · USCancer Research And Biostatistics · USSimon Fraser University · CAUniversity of KwaZulu-Natal · ZA

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
Addressing psychosocial comorbidities in HIV treatment and preventionK24MH094214 · NIMH · UNIVERSITY OF MIAMI CORAL GABLES · PI SAFREN, STEVEN A · 2011 to 2015
$858k
Periconception HIV risk reduction for HIV-discordant couples in UgandaK23MH095655 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI MATTHEWS, LYNN T · 2011 to 2015
$854k
Perinatal Depression, Stigma, Social Capital Utilization and PMTCT AdherenceK23MH096651 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI PSAROS, CHRISTINA · 2012 to 2016
$843k
Mentoring Patient Oriented Adherence Research in UgandaK24MH087227 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BANGSBERG, DAVID ROY · 2009 to 2013
$776k
NIAID NIH HHS P30 AI060354NIMH NIH HHS K23 MH095655NIMH NIH HHS K23 MH096651NIMH NIH HHS K24MH094214NIMH NIH HHS K24 MH87227Wellcome Trust
6 · The paper itself

Abstract

HIV-infected men and women who choose to conceive risk infecting their partners. To inform safer conception programs we surveyed HIV risk behavior prior to recent pregnancy amongst South African, HIV-infected women (N = 209) and men (N = 82) recruited from antenatal and antiretroviral clinics, respectively, and reporting an uninfected or unknown-HIV-serostatus pregnancy partner. All participants knew their HIV-positive serostatus prior to the referent pregnancy. Only 11 % of women and 5 % of men had planned the pregnancy; 40 % of women and 27 % of men reported serostatus disclosure to their partner before conception. Knowledge of safer conception strategies was low. Around two-thirds reported consistent condom use, 41 % of women and 88 % of men reported antiretroviral therapy, and a third of women reported male partner circumcision prior to the referent pregnancy. Seven women (3 %) and two men (2 %) reported limiting sex without condoms to peak fertility. None reported sperm washing or manual insemination. Safer conception behaviors including HIV-serostatus disclosure, condom use, and ART at the time of conception were not associated with desired pregnancy. In light of low pregnancy planning and HIV-serostatus disclosure, interventions to improve understandings of serodiscordance and motivate mutual HIV-serostatus disclosure and pregnancy planning are necessary first steps before couples or individuals can implement specific safer conception strategies.

Indexed as

Risk-TakingSafe SexSexual PartnersAdultCondomsFemaleHIV InfectionsHIV SeropositivityHumansMalePregnancySexual BehaviorSouth AfricaYoung AdultPMTCTSafer conceptionSerodiscordant couplesSouth Africa

Identifiers

PMID26080688
PMCPMC4926315
OpenAlexW563018246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.