Evidence map›Paper›PMID 26080431›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2015

Improving efficacy of the combination between antiangiogenic and chemotherapy: Time for mathematical modeling support.

Joseph Ciccolini, Sébastien Benzekry, Bruno Lacarelle, Dominique Barbolosi, Fabrice Barlési

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Reply to Ciccolini et al.: Using mathematical modeling to predict response to antiangiogenic therapy in cancer patients.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Joseph CiccoliniSMARTc Unit, Pharmacokinetics Laboratory, Inserm S_911 CRO2 Aix Marseille University, and La Timone University Hospital of Marseille, 13000 Marseille, France; fabrice.barlesi@ap-hm.fr.
Sébastien BenzekryModelling, Control, and Computations Unit, Institut National de Recherche en Informatique et en Automatique, 33000 Bordeaux, France;
Bruno LacarelleSMARTc Unit, Pharmacokinetics Laboratory, Inserm S_911 CRO2 Aix Marseille University, and La Timone University Hospital of Marseille, 13000 Marseille, France; Clinical Pharmacokinetics Laboratory, Assistance Publique, Hopitaux de Marseille, 13000 Marseille, France;
Dominique BarbolosiSMARTc Unit, Pharmacokinetics Laboratory, Inserm S_911 CRO2 Aix Marseille University, and La Timone University Hospital of Marseille, 13000 Marseille, France;
Fabrice BarlésiSMARTc Unit, Pharmacokinetics Laboratory, Inserm S_911 CRO2 Aix Marseille University, and La Timone University Hospital of Marseille, 13000 Marseille, France; Multidisciplinary Oncology and Therapeutic Innovations Unit, Nord University Hospital of Marseille, 13000 Marseille, France fabrice.barlesi@ap-hm.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Angiogenesis InhibitorsAntibodies, Monoclonal, HumanizedAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, Non-Small-Cell LungFemaleHumansLung NeoplasmsMaleNeovascularization, PathologicVascular Endothelial Growth Factor AAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedVascular Endothelial Growth Factor A

Identifiers

PMID26080431
PMCPMC4500227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.