ArticleEmerging infectious diseases2015
Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013.
Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Spatio-temporal trends of artemisinin-based combination therapy efficacy from 2010 to 2024 in sub-Saharan Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Pooled it
- A Narrative Review on the Prevalence ofTropical medicine and infectious disease · 2025Review
- Emerging threat of artemisinin partial resistance markers (pfk13 mutations) in Plasmodium falciparum parasite populations in multiple geographical locations in high transmission regions of Uganda.Malaria journal · 2024Article
- Transcriptomic analyses of differentially expressed human genes, micro RNAs and long-non-coding RNAs in severe, symptomatic and asymptomatic malaria infection.Scientific reports · 2024Article
- An overview of artemisinin-resistant malaria and associated Pfk13 gene mutations in Central Africa.Parasitology research · 2024Review
- Day 3 parasitemia andmedRxiv : the preprint server for health sciences · 2024Article
- Article
- Screening for K13-Propeller Mutations Associated with Artemisinin Resistance in Plasmodium falciparum in Yambio County (Western Equatoria State, South Sudan).The American journal of tropical medicine and hygiene · 2023Article
- Parasite proteostasis and artemisinin resistance.Research square · 2023Article
- Clinical and Biological Characteristics of Severe Malaria in Children under 5 Years Old in Benin.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Article
- An analysis ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Review
- Adherence to Dihydroartemisinin + Piperaquine Treatment Regimen in Low and High Endemic Areas in Indonesia.Journal of tropical medicine · 2022Article
- A Proteasome Mutation SensitizesACS infectious diseases · 2021Article
- Possible mechanisms of the hypoglycaemic effect of artesunate: Gender implication.Metabolism open · 2021Article
- Limited Polymorphism inInfection and drug resistance · 2021Article
- Antimalarial Drug Resistance and Implications for the WHO Global Technical Strategy.Current epidemiology reports · 2021Review
- Article
- Identification of Mutations in Antimalarial Resistance GeneTropical medicine and infectious disease · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Plasmodium falciparum resistance to artemisinin derivatives is emerging in Asia. We examined molecular markers of resistance in 78 children in Uganda who had severe malaria and were treated with intravenous artesunate. We observed in the K13-propeller domain, A578S, a low-frequency (3/78), nonsynonymous, single-nucleotide polymorphism associated with prolonged parasite clearance.
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Registered trials
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