ArticlePloS one2015
Barratt Impulsivity and Neural Regulation of Physiological Arousal.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 41 citations in OpenAlex.
- Review: Suicide and its relationship to aggression and impulsivity.Cognitive, affective & behavioral neuroscience · 2025Review
- Interacting immediate and long-term action regulation in suicidal behavior.Journal of mood and anxiety disorders · 2025Article
- Online and Offline Aggressive Behaviors in Adolescence: The Role of Self-Regulatory Self-Efficacy Beliefs.Behavioral sciences (Basel, Switzerland) · 2024Article
- Loss and Frontal Striatal Reactivities Characterize Alcohol Use Severity and Rule-Breaking Behavior in Young Adult Drinkers.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Gray matter volumes of the insula and anterior cingulate cortex and their dysfunctional roles in cigarette smoking.Addiction neuroscience · 2022Article
- Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction.Biological psychiatry global open science · 2021Article
- Differences in resting-state functional connectivity according to the level of impulsiveness in patients with internet gaming disorder.Journal of behavioral addictions · 2021Article
- Brain Connectivity, and Hormonal and Behavioral Correlates of Sustained Weight Loss in Obese Patients after Laparoscopic Sleeve Gastrectomy.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Abnormal Functional Connectivity of the Amygdala in Mild Cognitive Impairment Patients With Depression Symptoms Revealed by Resting-State fMRI.Frontiers in psychiatry · 2021Article
- The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impact on Translational Neuroimaging.Frontiers in systems neuroscience · 2020Review
- Striatal functional connectivity in chronic ketamine users: a pilot study.The American journal of drug and alcohol abuse · 2020Article
- Cue-elicited craving, thalamic activity, and physiological arousal in adult non-dependent drinkers.Journal of psychiatric research · 2019Article
- Social anxiety, posterior insula activation, and autonomic response during self-initiated action in a Cyberball game.Journal of affective disorders · 2019Article
- Interactions of immediate and long-term action regulation in the course and complications of bipolar disorder.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Could Alcohol Abuse Drive Intimate Partner Violence Perpetrators' Psychophysiological Response to Acute Stress?International journal of environmental research and public health · 2018Article
- Response inhibition and fronto-striatal-thalamic circuit dysfunction in cocaine addiction.Drug and alcohol dependence · 2018Article
- Thalamic Cortical Error-Related Responses in Adult Social Drinkers: Sex Differences and Problem Alcohol Use.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Exploring Age-Related Changes in Resting State Functional Connectivity of the Amygdala: From Young to Middle Adulthood.Frontiers in aging neuroscience · 2018Article
- The effects of methylphenidate on cerebral responses to conflict anticipation and unsigned prediction error in a stop-signal task.Journal of psychopharmacology (Oxford, England) · 2016Article
- Lateral-Medial Dissociation in Orbitofrontal Cortex-Hypothalamus Connectivity.Frontiers in human neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
Abstract
backgroundTheories of personality have posited an increased arousal response to external stimulation in impulsive individuals. However, there is a dearth of studies addressing the neural basis of this association.
methodsWe recorded skin conductance in 26 individuals who were assessed with Barratt Impulsivity Scale (BIS-11) and performed a stop signal task during functional magnetic resonance imaging. Imaging data were processed and modeled with Statistical Parametric Mapping. We used linear regressions to examine correlations between impulsivity and skin conductance response (SCR) to salient events, identify the neural substrates of arousal regulation, and examine the relationship between the regulatory mechanism and impulsivity.
resultsAcross subjects, higher impulsivity is associated with greater SCR to stop trials. Activity of the ventromedial prefrontal cortex (vmPFC) negatively correlated to and Granger caused skin conductance time course. Furthermore, higher impulsivity is associated with a lesser strength of Granger causality of vmPFC activity on skin conductance, consistent with diminished control of physiological arousal to external stimulation. When men (n = 14) and women (n = 12) were examined separately, however, there was evidence suggesting association between impulsivity and vmPFC regulation of arousal only in women.
conclusionsTogether, these findings confirmed the link between Barratt impulsivity and heightened arousal to salient stimuli in both genders and suggested the neural bases of altered regulation of arousal in impulsive women. More research is needed to explore the neural processes of arousal regulation in impulsive individuals and in clinical conditions that implicate poor impulse control.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.