ArticleFertility and sterility2015
Endometrial pattern, but not endometrial thickness, affects implantation rates in euploid embryo transfers.
Article in Fertility and sterility, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The role played by granulocyte colony stimulating factor (G-CSF) on women submitted to in vitro fertilization associated with thin endometrium: systematic review.JBRA assisted reproduction · 2020Pooled it
- Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2016Pooled it
- Comparison of tamoxifen and hormone replacement cycle (HRT) in frozen embryo transfer. A randomized controlled trial.JBRA assisted reproduction · 2023Trial
- Cumulative Live Birth Rate in Patients With Thin Endometrium: A Real-World Single-Center Experience.Frontiers in endocrinology · 2020Trial
- The endometrial preparation for frozen-thawed euploid blastocyst transfer: a prospective randomized trial comparing clinical results from natural modified cycle and exogenous hormone stimulation with GnRH agonist.Journal of assisted reproduction and genetics · 2016Trial
- Potential and Challenges of Menstrual Blood-derived Mesenchymal Stem Cells/Stromal Cells in Treating Female Infertility: A Recent Review.Reproductive sciences (Thousand Oaks, Calif.) · 2026Review
- Definition of thin endometrium from the perspective of miscarriage following frozen embryo transfer: a retrospective cohort study of 15,979 pregnancies.BMC pregnancy and childbirth · 2026Article
- Association between endometrial thickness and cumulative live birth rate in one oocyte-retrieval cycle: a retrospective cohort study including 26,127 patients.BMC pregnancy and childbirth · 2026Article
- Do hypoechoic endometrial cystic appearances before embryo transfer affect pregnancy rates in frozen-thawed cycles?PloS one · 2026Article
- Article
- Investigating the Effect of Endometrial Thickness Changes and Compaction on the Fertility Rate of Patients Undergoing ART: A Prospective Study.Journal of obstetrics and gynaecology of India · 2025Article
- Multi-modality imaging technologies and machine learning for non-invasive, precise assessment of rabbit endometrium.Biomedical optics express · 2025Article
- Acupuncture as an adjunct therapy for enhancing endometrial receptivity in female infertility: a literature review.Frontiers in physiology · 2025Review
- Gonadotropin Releasing Hormone Agonists Combined with Hormone Replacement Therapy Significantly Improves Reproductive Outcomes for Patients with Thin Endometrium and Intramural Fibroids in Frozen Embryo Transfer Cycles.Drug design, development and therapy · 2025Article
- Immune-related gene signatures of thin endometrium: a transcriptomic and single-cell study.Frontiers in endocrinology · 2025Observational
- Determining Factors Influencing The Successful Embryo Transfer and Pregnancy during The Frozen Cycle ofInternational journal of fertility & sterility · 2024Article
- High androgen level during controlled ovarian stimulation cycle impairs endometrial receptivity in PCOS patients.Scientific reports · 2024Article
- The embryo stage at fresh ET does not affect the cumulative live birth rate in women with a thin endometrium: a retrospective matched-controlled cohort study.Frontiers in endocrinology · 2024Article
- An endometrial receptivity scoring system evaluated by ultrasonography in patients undergoing frozen-thawed embryo transfer: a prospective cohort study.Frontiers in medicine · 2024Article
- A new method for endometrial dating using computerized virtual pathology.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveTo evaluate the relationship of endometrial thickness (EnT) and endometrial pattern (EnP) to euploid embryo transfer (ET) outcomes.
designRetrospective cohort.
settingPrivate academic clinic. PATIENT(S): Patients (n = 277; age 36.1 ± 4.0 years) whose embryos (n = 476) underwent aneuploidy screening with fresh (n = 176) or frozen (n = 180) ET from July 2010 to March 2014. INTERVENTION(S): The EnT and EnP were measured on trigger day and at ET. Patients were stratified by age and cycle type (fresh or frozen). Cycle data were combined at trigger day, but separated at ET day. MAIN OUTCOME MEASURE(S): Outcome measures were implantation rate, pregnancy rate, and clinical pregnancy rate. Analysis was conducted using χ(2) analysis and Fisher's exact test. RESULT(S): A total of 234 gestational sacs, 251 pregnancies, and 202 clinical pregnancies resulted from 356 cycles. The EnT (9.6 ± 1.8 mm; range: 5-15 mm) at trigger day (n = 241 cycles), as a continuous or categorical variable (≤8 vs. >8 mm), was not associated with implantation rate, pregnancy rate, or clinical pregnancy rate. The EnT at day of fresh ET (9.7 ± 2.2 mm; range: 4.4-17.9 mm) (n = 176 cycles) or frozen ET (9.1 ± 2.1 mm; range: 4.2-17.7 mm) (n = 180 cycles) was not associated with implantation rate, pregnancy rate, or clinical pregnancy rate. Type 3 EnP at trigger day was associated with increased serum progesterone at trigger and a decreased implantation rate, compared with type 2 EnP. The EnP at fresh or frozen ET was not associated with implantation rate, pregnancy rate, or clinical pregnancy rate. CONCLUSION(S): Within the study population, EnT was not significantly associated with clinical outcomes of euploid ETs. A type 3 EnP at trigger day suggests a prematurely closed window of implantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.