Evidence map›Paper›PMID 26078694›Full record

ArticleTurk pediatri arsivi2015

Comparison of selective head cooling therapy and whole body cooling therapy in newborns with hypoxic ischemic encephalopathy: short term results.

Aytuğ Atıcı, Yalçın Çelik, Selvi Gülaşı, Ali Haydar Turhan, Çetin Okuyaz, Mehmet Ali Sungur

Open access · bronzeAbstract read
In one paragraph

Article in Turk pediatri arsivi, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Neuroprotection by Therapeutic Hypothermia.Frontiers in neuroscience · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aytuğ AtıcıDepartment of Pediatrics, Division of Neanotology, Mersin University Faculty of Medicine, Mersin, Turkey.
Yalçın ÇelikDepartment of Pediatrics, Division of Neanotology, Mersin University Faculty of Medicine, Mersin, Turkey.
Selvi GülaşıDepartment of Pediatrics, Division of Neanotology, Mersin University Faculty of Medicine, Mersin, Turkey.
Ali Haydar TurhanDepartment of Pediatrics, Division of Neanotology, Mersin University Faculty of Medicine, Mersin, Turkey.
Çetin OkuyazDepartment of Pediatrics, Division of Pediatric Neurology, Mersin University, Faculty of Medicine, Mersin, Turkey.
Mehmet Ali SungurDepartment of Biostatistics and Medical Informatics, Mersin University Faculty of Medicine, Mersin, Turkey.
Mersin Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn this study, it was aimed to investigate which method was superior by applying selective head cooling or whole body cooling therapy in newborns diagnosed with moderate or severe hypoxic ischemic encephalopathy. MATERIALS AND

methodNewborns above the 35th gestational age diagnosed with moderate or severe hypoxic ischemic encephalopathy were included in the study and selective head cooling or whole body cooling therapy was performed randomly. The newborns who were treated by both methods were compared in terms of adverse effects in the early stage and in terms of short-term results. Ethics committee approval was obtained for the study (06.01.2010/35).

resultsFifty three babies diagnosed with hypoxic ischemic encephalopathy were studied. Selective head cooling was applied to 17 babies and whole body cooling was applied to 12 babies. There was no significant difference in terms of adverse effects related to cooling therapy between the two groups. When the short-term results were examined, it was found that the hospitalization time was 34 (7-65) days in the selective head cooling group and 18 (7-57) days in the whole body cooling group and there was no significant difference between the two groups (p=0.097). Four patients in the selective head cooling group and two patients in the whole body cooling group were discharged with tracheostomy because of the need for prolonged mechanical ventilation and there was no difference between the groups in terms of discharge with tracheostomy (p=0.528). Five patients in the selective head cooling group and three patients in the whole body cooling group were discharged with a gastrostomy tube because they could not be fed orally and there was no difference between the groups in terms of discharge with a gastrostomy tube (p=0.586). One patient who was applied selective head cooling and one patient who was applied whole body cooling died during hospitalization and there was no difference between the groups in terms of mortality (p=0.665).

conclusionsThere is no difference between the methods of selective head cooling and whole body cooling in terms of adverse effects and short-term results.

Indexed as

Hypoxic ischemic encephalopathyselective head coolingwhole body cooling

Identifiers

PMID26078694
PMCPMC4462329
OpenAlexW2160251426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.