ArticleWorld journal of gastroenterology2015
Clinical impact of preoperative acute pancreatitis in patients who undergo pancreaticoduodenectomy for periampullary tumors.
Article in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Pancreaticoduodenectomy for Ampullary Carcinoma after Clinical Resolution of Necrotizing Pancreatitis with Giant Walled-Off Necrosis: A Case Report.Surgical case reports · 2026Article
- Article
- Is robotic pancreaticoduodenectomy non-inferior to open pancreaticoduodenectomy in patients with high PD-ROBOSCORE?Surgical endoscopy · 2025Article
- Staging Computed Tomography Parameters Predict the Need for Vein Resection during Pancreaticoduodenectomy in Resectable Pancreatic Ductal Adenocarcinoma.Diagnostics (Basel, Switzerland) · 2024Article
- Review
- Article
- Clinical characteristic and pathogenesis of tumor-induced acute pancreatitis: a predictive model.BMC gastroenterology · 2022Article
- The Relationship between Acute and Chronic Pancreatitis with Pancreatic Adenocarcinoma: Review.Diseases (Basel, Switzerland) · 2021Review
- Does Preoperative Acute Pancreatitis Inevitably Delay Pancreatoduodenectomy in Patients with Periampullary Tumors?Cancers · 2021Article
- Pancreatoduodenectomy for Periampullary Tumors Presenting with Acute Pancreatitis.Gastroenterology research and practice · 2020Article
- Recurrence and survival after surgery for pancreatic cancer with or without acute pancreatitis.World journal of gastroenterology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the impact of preoperative acute pancreatitis (PAP) on the surgical management of periampullary tumors.
methodsFifty-eight patients with periampullary tumors and PAP were retrospectively analyzed. Thirty-four patients who underwent pancreaticoduodenectomy (PD) and 4 patients who underwent total pancreatectomy were compared with a control group of 145 patients without PAP during the same period.
resultsThe preoperative waiting time was significantly shorter for the concomitant PAP patients who underwent a resection (22.4 d vs 54.6 d, P < 0.001) compared to those who did not. The presence of PAP significantly increased the rate of severe complications (Clavien grade 3 or higher) (17.6% vs 4.8%, P = 0.019) and lengthened the hospital stay (19.5 d vs 14.5 d, P = 0.006). A multivariate logistic regression analysis revealed that PAP was an independent risk factor for postoperative pancreatic fistula (OR = 2.91; 95%CI: 1.10-7.68; P = 0.032) and severe complications (OR = 4.70; 95%CI: 1.48-14.96; P = 0.009) after PD. There was no perioperative mortality.
conclusionPAP significantly increases the incidence of severe complications and lengthens the hospital stay following PD. PD could be safely performed in highly selective patients with PAP.
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