ArticleBehavioural neurology2015
Patterns of Objective and Subjective Burden of Informal Caregivers in Multiple Sclerosis.
Article in Behavioural neurology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Caregiver Burden of Spinal Muscular Atrophy: A Systematic Review.PharmacoEconomics · 2023Pooled it
- Understanding Diverse Caregiver Experiences and Their Impact on Caregiver Burden in Multiple Sclerosis.International journal of MS care · 2025Article
- Masculinity in Caregiving: Impact on Quality of Life and Self-Stigma in Caregivers of People with Multiple Sclerosis.Healthcare (Basel, Switzerland) · 2025Article
- Profile and burden of the family caregiver: the caring experience in multiple sclerosis. An observational study.BMC psychology · 2024Observational
- Design and psychometrics of the family caregivers burnout inventory of older adults with chronic disease.Frontiers in public health · 2024Article
- The Clinical and Economic Impact of Employees Who Are Care Partners of Patients with Multiple Sclerosis by Disease Severity.Journal of health economics and outcomes research · 2023Article
- Caregiving Situation as a Predictor of Subjective Caregiver Burden: Informal Caregivers of Older Adults during the COVID-19 Pandemic.International journal of environmental research and public health · 2022Article
- Challenges of caregiving to neurological patients.Wiener medizinische Wochenschrift (1946) · 2021Review
- Psychoeducational Interventions for Caregivers of Persons With Multiple Sclerosis: Protocol for a Randomized Trial.JMIR research protocols · 2021Article
- Family Functioning and Multiple Sclerosis: Study Protocol of a Multicentric Italian Project.Frontiers in psychology · 2021Article
- Italian validation of the caregiving tasks in multiple sclerosis scale (CTiMSS).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Caregiver Burden in Multiple Sclerosis: Recent Trends and Future Directions.Current neurology and neuroscience reports · 2020Review
- Psychological Shift in Partners of People with Multiple Sclerosis Who Undertake Lifestyle Modification: An Interpretive Phenomenological Study.Frontiers in psychology · 2018Article
- The multidimensional burden of informal caregivers in primary malignant brain tumor.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Multiple Sclerosis Adult Day Programs and Health-Related Quality of Life of Persons with Multiple Sclerosis and Informal Caregivers.International journal of MS careArticle
- Fatigue and Mood States in Nursing Home and Nonambulatory Home-Based Patients with Multiple Sclerosis.International journal of MS careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHome care for patients with Multiple Sclerosis (MS) relies largely on informal caregivers (ICs). Methods. We assessed ICs objective burden (Resource Utilization in Dementia measuring informal care time (ICT)) and ICs subjective burden (Zarit Burden Inventory (ZBI)).
resultsICs (N = 99) were spouses (70%), mean age 52 years, assisting disabled patients with a mean EDSS (Expanded Disability Status Scale) of 5.5, with executive dysfunction (mean DEX (Dysexecutive questionnaire) of 25) and a duration of MS ranging from 1 to 44 years.
objectiveburden was high (mean ICT = 6.5 hours/day), mostly consisting of supervision time. Subjective burden was moderate (mean ZBI = 27.3). Multivariate analyses showed that both burdens were positively correlated with higher levels of EDSS and DEX, whereas coresidency and IC's female gender correlated with objective burden only and IC's poor mental health status with subjective burden only. When considering MS aggressiveness, it appeared that both burdens were not correlated with a higher duration of MS but rather increased for patients with severe and early dysexecutive function and for patients classified as fast progressors according to the Multiple Sclerosis Severity Score.
conclusionEvaluation of MS disability course and IC's personal situation is crucial to understand the burden process and to implement adequate interventions in MS.
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