Evidence map›Paper›PMID 26078341›Full record

ArticlePhilosophical transactions. Series A, Mathematical, physical, and engineering sciences2015

Molecular ping-pong Game of Life on a two-dimensional DNA origami array.

N Jonoska, N C Seeman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Philosophical transactions. Series A, Mathematical, physical, and engineering sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

N JonoskaDepartment of Mathematics and Statistics, University of South Florida, Tampa, FL, USA jonoska@mail.usf.edu.
N C SeemanDepartment of Chemistry, New York University, New York, NY, USA.

Funding

Physical Chemistry of Recombinational IntermediatesR37GM029554 · NIGMS · NEW YORK UNIVERSITY · PI SEEMAN, NADRIAN C. · 2005 to 2012
$2.7M
RNA-guided Genome Rearrangement: Experiments Coupled with Discrete ModelsR01GM109459 · NIGMS · UNIVERSITY OF SOUTH FLORIDA · PI JONOSKA, NATASHA · 2013 to 2017
$2.0M
PHYSICAL CHEMISTRY OF RECOMBINATIONAL INTERMEDIATESR01GM029554 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI SEEMAN, NADRIAN C. · 1985 to 2004
$1.4M
NIGMS NIH HHS GM-29554NIGMS NIH HHS R01 GM109459NIGMS NIH HHS R01GM109459-01
6 · The paper itself

Abstract

We propose a design for programmed molecular interactions that continuously change molecular arrangements in a predesigned manner. We introduce a model where environmental control through laser illumination allows platform attachment/detachment oscillations between two floating molecular species. The platform is a two-dimensional DNA origami array of tiles decorated with strands that provide both, the floating molecular tiles to attach and to pass communicating signals to neighbouring array tiles. In particular, we show how algorithmic molecular interactions can control cyclic molecular arrangements by exhibiting a system that can simulate the dynamics similar to two-dimensional cellular automata on a DNA origami array platform.

Indexed as

Nucleic Acid ConformationAlgorithmsComputer SimulationDNALasersModels, BiologicalMolecular ConformationOscillometrySignal TransductionDNAcellular automataDNA origamiDNA signalsGame of Lifelaser illumination assembly controloscillating DNA attachments

Identifiers

PMID26078341
PMCPMC7398061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.