Evidence map›Paper›PMID 26078120›Full record

ArticleInternational journal of clinical pharmacy2015

Recommendations to support deprescribing medications late in life.

Adam Todd, Holly M Holmes

Abstract read
In one paragraph

Article in International journal of clinical pharmacy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Palliative Care: A Primary Care Pharmacist Perspective.Pharmacy (Basel, Switzerland) · 2022
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Deprescribing in palliative care.Clinical medicine (London, England) · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review of structured guides for deprescribing.European journal of hospital pharmacy : science and practice · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adam ToddDivision of Pharmacy, School of Medicine, Pharmacy and Health, Durham University, Queen's Campus, Stockton-on-Tees, UK. adam.todd@durham.ac.uk.
Holly M HolmesDepartment of General Internal Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Funding

Medication Adherence Among Older Persons Enrolled in Medicare Part DK23AG038476 · NIA · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HOLMES, HOLLY M. · 2011 to 2015
$653k
NIA NIH HHS K23 AG038476
6 · The paper itself

Abstract

It is widely acknowledged that patients-particularly those late in life-are frequently exposed to the harms of medication. To minimize these harms, several frameworks have been developed by which prescribing can be optimized. In the context of diminishing life expectancy, these frameworks can be used to reduce medications that are no longer necessary, but appear to fall short of actual guidelines that incorporate a consideration of stopping medications. In this commentary, we present recommendations that could be incorporated into prescribing processes for all healthcare professionals and, ultimately, used to support the rationalization or deprescribing of medication in diminished life expectancy. We frame these recommendations in the same context as guidance for the initiation and discontinuation of implantable cardiac devices and argue that the two processes-with regards to decision-making-should be the same. We present our recommendations with preventive medication use in mind, and use statin therapy as an illustrative example.

Indexed as

DeprescriptionsAge FactorsDrug PrescriptionsHumansInappropriate PrescribingLife ExpectancyPolypharmacyDeprescribingPolypharmacyRationalizing medications

Identifiers

PMID26078120
PMCPMC4682203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.