Evidence map›Paper›PMID 26077953›Full record

ArticleJournal of autism and developmental disorders2015

Stoppage in Autism Spectrum Disorders.

Therese K Grønborg, Stefan N Hansen, Svend V Nielsen, Axel Skytthe, Erik T Parner

Abstract readTwin Study
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Recurrence Risk of Autism in Siblings and Cousins: A Multinational, Population-Based Study.Journal of the American Academy of Child and Adolescent Psychiatry · 2019
    Article
  5. Article
  6. Provision of Genetic Services for Autism and its Impact on Spanish Families.Journal of autism and developmental disorders · 2017
    Article
  7. Article
  8. Clinical Genetic Aspects of ASD Spectrum Disorders.International journal of molecular sciences · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Therese K GrønborgSection for Biostatistics, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000, Aarhus C, Denmark. therese@ph.au.dk.
Stefan N HansenSection for Biostatistics, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000, Aarhus C, Denmark.
Svend V NielsenDepartment of Mathematics, Aarhus University, Aarhus C, Denmark.
Axel SkyttheThe Danish Twin Registry, Epidemiology, Biostatistics and Biodemography, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Erik T ParnerSection for Biostatistics, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000, Aarhus C, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stoppage refers to changes in reproductive behavior following the birth of a child with a severe disease. The presence of stoppage can bias estimates of sibling recurrence risk if not properly addressed. If stoppage occurs non-randomly (differential stoppage), it is possibly an additional source of bias in sibling recurrence risk estimation. This study investigated whether stoppage occurs in Danish families with a firstborn child diagnosed with autism spectrum disorders, and if stoppage was differential. We found that stoppage occurs moderately in Danish families affected by autism spectrum disorders, and that stoppage is differential. However, differential stoppage is a minor source of estimation bias in Danish sibling recurrence risk studies of autism spectrum disorders.

Indexed as

RegistriesAdolescentAdultAutism Spectrum DisorderBiasBirth OrderChildDenmarkFemaleHumansKaplan-Meier EstimateMaleReproductive BehaviorSiblingsAutism spectrum disorderSibling recurrence riskStoppage

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.