Evidence map›Paper›PMID 26077550›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2016

Healthcare costs associated with cardiovascular events in patients with hyperlipidemia or prior cardiovascular events: estimates from Swedish population-based register data.

S Hallberg, S R Gandra, K M Fox, J Mesterton, J Banefelt, G Johansson, L-Å Levin, P Sobocki

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Hospital and Institutionalisation Care Costs after Limb and Visceral Ischaemia Benchmarked Against Stroke: Long-Term Results of a Population Based Cohort Study.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2018
    Article
  15. Article
  16. Article
  17. Article
  18. Global & regional health technology assessment
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S HallbergQuantify Research, Hantverkargatan 8, 112 21, Stockholm, Sweden. sara.hallberg@quantifyresearch.com.ORCID http://orcid.org/0000-0003-2164-8060
S R GandraAmgen Inc., Thousand Oaks, CA, USA.
K M FoxStrategic Healthcare Solutions, LLC, Baltimore, MD, USA.
J MestertonQuantify Research, Hantverkargatan 8, 112 21, Stockholm, Sweden.
J BanefeltQuantify Research, Hantverkargatan 8, 112 21, Stockholm, Sweden.
G JohanssonDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
L-Å LevinDepartment of Medical and Health Sciences, Linköping University, Linköping, Sweden.
P SobockiLIME/Medical Management Centre, Karolinska Institute, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo estimate healthcare costs of new cardiovascular (CV) events (myocardial infarction, unstable angina, revascularization, ischemic stroke, transient ischemic attack, heart failure) in patients with hyperlipidemia or prior CV events.

methodsA retrospective population-based cohort study was conducted using Swedish national registers and electronic medical records. Patients with hyperlipidemia or prior CV events were stratified into three cohorts based on CV risk level: history of major cardiovascular disease (CVD), coronary heart disease (CHD) risk-equivalent, and low/unknown risk. Propensity score matching was applied to compare patients with new events to patients without new events for estimation of incremental costs of any event and by event type.

resultsA CV event resulted in increased costs over 3 years of follow-up, with the majority of costs occurring in the 1st year following the event. The mean incremental cost of patients with a history of major CVD (n = 6881) was €8588 during the 1st year following the event. This was similar to that of CHD risk-equivalent patients (n = 3226; €6663) and patients at low/unknown risk (n = 2497; €8346). Ischemic stroke resulted in the highest 1st-year cost for patients with a history of major CVD and CHD risk-equivalent patients (€10,194 and €9823, respectively); transient ischemic attack in the lowest (€3917 and €4140). Incremental costs remained elevated in all cohorts during all three follow-up years, with costs being highest in the major CVD history cohort.

conclusionsHealthcare costs of CV events are substantial and vary considerably by event type. Incremental costs remain elevated for several years after an event.

Indexed as

AgedAged, 80 and overCardiovascular DiseasesCause of DeathComorbidityCoronary DiseaseFemaleHealth ExpendituresHealth ServicesHospitalizationHumansHyperlipidemiasMaleMiddle AgedModels, EconometricPrescription FeesBurden of illnessCardiovascularCostsCVDHyperlipidemiaResource use

Identifiers

PMID26077550
PMCPMC4869759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.