Evidence map›Paper›PMID 26077459›Full record

Trial reportTrials2015

The effect of a therapeutic regimen of Traditional Chinese Medicine rehabilitation for post-stroke cognitive impairment: study protocol for a randomized controlled trial.

Jia Huang, Zhengkun Lin, Qin Wang, Feiwen Liu, Jiao Liu, Yunhua Fang, Shanjia Chen, Xiaoxuan Zhou, Wenjun Hong, Jinsong Wu and 5 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05231694 (Specific Stimulation Mode Electroacupuncture Combined With NGF for Recovery Period of Ischemic Stroke:Protocol for a Randomized Controlled Clinical Trial), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05231694 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Specific Stimulation Mode Electroacupuncture Combined With NGF for Recovery Period of Ischemic Stroke:Protocol for a Randomized Controlled Clinical Trial

TypeinterventionalSponsorThe Third Affiliated hospital of Zhejiang Chinese Medical UniversityRan2022 to 2025Enrolled288ConditionsIschemic StrokeArmsNerver growth factor (NGF) injection, Placebo injection, EA intervention, sham EA intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Jia HuangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. jasmine1874@163.com.
Zhengkun LinCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. yushu_860223@163.com.
Qin WangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. wangqin_8808@163.com.
Feiwen LiuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 591417095@qq.com.
Jiao LiuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 1773903011@qq.com.
Yunhua FangCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 1938655280@qq.com.
Shanjia ChenCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 946227821@qq.com.
Xiaoxuan ZhouCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 644493290@qq.com.
Wenjun HongCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 568703596@qq.com.
Jinsong WuCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. 61102547@qq.com.
Natalia Madrigal-MoraFriedrich-Alexander University Erlangen-Nuremberg, Schlossplatz 4, 91054, Erlangen, Germany. natalia.madrigal@fau.de.
Guohua ZhengCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. zhgh_1969@aliyun.com.
Shanli YangFujian University of Traditional Chinese Medicine Subsidiary Rehabilitation Hospital, No. 282 WUSI Road, Gulou, Fuzhou, 350003, China. 49688400@qq.com.
Jing TaoCollege of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, No. 1 Huatuo Road Shangjie Minhou, Fuzhou, 350122, China. taojing01@163.com.
Lidian ChenFujian Key Laboratory of Exercise Rehabilitation, No. 282 WUSI Road, Gulou, Fuzhou, 350003, China. lidianchen87@163.com.
Fujian University of Traditional Chinese Medicine · CNFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-stroke cognitive impairment (PSCI) lessens quality of life, restricts the rehabilitation of stroke, and increases the social and economic burden stroke imposes on patients and their families. Therefore effective treatment is of paramount importance. However, the treatment of PSCI is very limited. The primary aim of this protocol is to propose a lower cost and more effective therapy, and to confirm the long-term effectiveness of a therapeutic regimen of Traditional Chinese Medicine (TCM) rehabilitation for PSCI. METHODS/

designA prospective, multicenter, large sample, randomized controlled trial will be conducted. A total of 416 eligible patients will be recruited from seven inpatient and outpatient stroke rehabilitation units and randomly allocated into a therapeutic regimen of TCM rehabilitation group or cognitive training (CT) control group. The intervention period of both groups will last 12 weeks (30 minutes per day, five days per week). Primary and secondary outcomes will be measured at baseline, 12 weeks (at the end of the intervention), and 36 weeks (after the 24-week follow-up period). DISCUSSION: This protocol presents an objective design of a multicenter, large sample, randomized controlled trial that aims to put forward a lower cost and more effective therapy, and confirm the long-term effectiveness of a therapeutic regimen of TCM rehabilitation for PSCI through subjective and objective assessments, as well as highlight its economic advantages.

trial registrationThis trial was registered with the Chinese Clinical Trial Registry (identifier: ChiCTR-TRC-14004872 ) on 23 June 2014.

Indexed as

Acupuncture TherapyCognitionCognitive Behavioral TherapyStroke RehabilitationChinaClinical ProtocolsCognition DisordersCost-Benefit AnalysisHealth Care CostsHumansProspective StudiesResearch DesignSingle-Blind MethodStrokeTime FactorsTreatment Outcome

Identifiers

PMID26077459
PMCPMC4485558
OpenAlexW2129002581

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.