Evidence map›Paper›PMID 26077399›Full record

SynthesisThe Journal of rheumatology2015

Update on Outcome Measure Development for Large Vessel Vasculitis: Report from OMERACT 12.

Sibel Zehra Aydin, Haner Direskeneli, Antoine Sreih, Fatma Alibaz-Oner, Ahmet Gul, Sevil Kamali, Gulen Hatemi, Tanaz Kermani, Sarah L Mackie, Alfred Mahr and 6 more

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The Journal of rheumatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Arterial lesions in giant cell arteritis: A longitudinal study.Seminars in arthritis and rheumatism · 2019
    Article
  14. Review
  15. Unmet Needs in the Pathogenesis and Treatment of Vasculitides.Clinical reviews in allergy & immunology · 2018
    Review
  16. Evaluation of damage in giant cell arteritis.Rheumatology (Oxford, England) · 2018
    Article
  17. Article
  18. Article
  19. Review
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 6 countries.

Sibel Zehra AydinFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Haner DireskeneliFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Antoine SreihFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Fatma Alibaz-OnerFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Ahmet GulFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Sevil KamaliFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Gulen HatemiFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Tanaz KermaniFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Sarah L MackieFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Alfred MahrFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Alexa MearaFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Nataliya MilmanFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Heidi NugentFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Joanna RobsonFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Gunnar TomassonFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Peter A MerkelFrom the Division of Rheumatology, Koc University Faculty of Medicine, Istanbul; Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, and Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine, Istanbul, Turkey; Division of Rheumatology, University of California, Los Angeles, California, USA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Internal Medicine, University Paris Diderot, Paris, France; Division of Rheumatology, Ohio State University, Columbus, Ohio, USA; Division of Rheumatology, University of Ottawa, Ottawa, Ontario, Canada; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK; Department of Public Health Sciences, University of Iceland, Reykjavik, Iceland.S.Z. Aydin, MD, Associate Professor, Division of Rheumatology, Koc University Faculty of Medicine; H. Direskeneli, MD, Professor of Rheumatology, Division of Rheumatology, Marmara University Faculty of Medicine; A. Sreih, MD, Assistant Professor of Medicine, Division of Rheumatology, University of Pennsylvania; F. Alibaz-Oner, MD, Division of Rheumatology, Marmara University Faculty of Medicine; A. Gul, Professor, Division of Rheumatology, Istanbul University Istanbul Faculty of Medicine; S. Kamali, Professor, Division of Rheumatology, Marmara University Faculty of Medicine; G. Hatemi, Associate Professor, Division of Rheumatology, Istanbul University Cerrahpasa Faculty of Medicine; T. Kermani, MD, MS, Assistant Clinical Professor, Division of Rheumatology, University of California at Los Angeles; S.L. Mackie, BM, BCh, PhD, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; A. Mahr, MD, PhD, Professo
Istanbul University · TRUniversité Paris Cité · FRDélégation Paris 7 · FR

Funding

VCRC-VF FellowshipU54AR057319 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MERKEL, PETER A · 2009 to 2020
$12.5M
VASCULITIS CLINICAL RESEARCH NETWORK (VCRN): RARE DISEASEU54RR019497 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MERKEL, PETER A · 2003 to 2008
$6.1M
Vasculitis Outcome Measures: Development and ValidationU01AR051874 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI MERKEL, PETER A · 2005 to 2006
$386k
NCRR NIH HHS U54 RR019497NIAMS NIH HHS U01 AR051874NIAMS NIH HHS U01 AR51874NIAMS NIH HHS U54 AR057319
6 · The paper itself

Abstract

objectiveThe rarity of large vessel vasculitis (LVV) is a major factor limiting randomized controlled trials in LVV, resulting in treatment choices in these diseases that are guided mainly by observational studies and expert opinion. Further complicating trials in LVV is the absence of validated and meaningful outcome measures. The Outcome Measures in Rheumatology (OMERACT) vasculitis working group initiated the Large Vessel Vasculitis task force in 2009 to develop data-driven, validated outcome tools for clinical investigation in LVV. This report summarizes the progress that has been made on a disease activity assessment tool and patient-reported outcomes in LVV as well as the group's research agenda.

methodsThe OMERACT LVV task force brought an international group of investigators and patient research partners together to work collaboratively on developing outcome tools. The group initially focused on disease activity assessment tools in LVV. Following a systematic literature review, an international Delphi exercise was conducted to obtain expert opinion on principles and domains for disease assessment. The OMERACT vasculitis working group's LVV task force is also conducting qualitative research with patients, including interviews, focus groups, and engaging patients as research partners, all to ensure that the approach to disease assessment includes measures of patients' perspectives and that patients have input into the research agenda and process.

resultsThe preliminary results of both the Delphi exercise and the qualitative interviews were discussed at the OMERACT 12 (2014) meeting and the completion of the analyses will produce an initial set of domains and instruments to form the basis of next steps in the research agenda.

conclusionThe research agenda continues to evolve, with the ultimate goal of developing an OMERACT-endorsed core set of outcome measures for use in clinical trials of LVV.

Indexed as

Outcome Assessment, Health CareQualitative ResearchConsensus Statements as TopicDelphi TechniqueFemaleFocus GroupsGiant Cell ArteritisHumansMalePractice Guidelines as TopicRadiographySeverity of Illness IndexTakayasu ArteritisVasculitisGIANT CELL ARTERITISLARGE VESSELOUTCOMESTAKAYASU ARTERITISVASCULITIS

Identifiers

PMID26077399
PMCPMC4668221
OpenAlexW4238357104

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