Evidence map›Paper›PMID 26077140›Full record

ArticleInternational journal of clinical oncology2016

Use of preoperative performance status and hemoglobin concentration to predict overall survival for patients aged ≥ 75 years after radical cystectomy for treatment of bladder cancer.

Takahiko Hara, Hideyasu Matsuyama, Yoriaki Kamiryo, Shigeaki Hayashida, Norio Yamamoto, Takahito Nasu, Keiji Joko, Yoshikazu Baba, Akinobu Suga, Mitsutaka Yamamoto and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in International journal of clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Takahiko HaraDepartment of Urology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan. hara-t@masuda.jrc.or.jp.
Hideyasu MatsuyamaDepartment of Urology, Graduate School of Medicine, Yamaguchi University, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Yoriaki KamiryoDepartment of Urology, Shimonoseki Saisekai Toyoura Hospital, 7-3 Kogushi, Toyoura, Shiomonoseki, Yamaguchi, 759-6302, Japan.
Shigeaki HayashidaDepartment of Urology and Nephrology, Tokuyama Central Hospital, 1-1 Takada, Shunan, Yamaguchi, 745-8522, Japan.
Norio YamamotoDepartment of Urology, Tokuyama Medical Association Hospital, 6-28 Higashiyama, Shunan, Yamaguchi, 745-0846, Japan.
Takahito NasuDepartment of Urology and Nephrology, Tokuyama Central Hospital, 1-1 Takada, Shunan, Yamaguchi, 745-8522, Japan.
Keiji JokoDepartment of Urology, Saiseikai Yamaguchi General Hospital, 2-11 Midorimachi, Yamaguchi, Yamaguchi, 753-0078, Japan.
Yoshikazu BabaDepartment of Urology, Shuto General Hospital, 1000-1 Kokaisaku, Yanai, Yamaguchi, 742-0032, Japan.
Akinobu SugaDepartment of Urology, Yamaguchi Red Cross Hospital, 53-1 Hachimanbaba, Yamaguchi, Yamaguchi, 753-8519, Japan.
Mitsutaka YamamotoDepartment of Urology, Yamaguchi Grand Medical Center, Hofu, 77 Osaki, Yamaguchi, 747-8511, Japan.
Akihiko AokiDepartment of Urology, Masuda Red Cross Hospital, I 103-1 Otoyoshi-chou, Masuda, Shimane, 698-8501, Japan.
Kimio TakaiDepartment of Urology, Saiseikai Shimonoseki General Hospital, 8-5-1 Yasuoka, Shomonoseki, Yamaguchi, 759-6603, Japan.
Satoru YoshihiroDepartment of Urology, Shimonoseki City Hospital, 1-13-1 Koyo, Shimonoseki, Yamaguchi, 750-8520, Japan.
Motohiko KonishiDepartment of Urology, Shunan City Shinnanyo Hospital, 2-3-15 Miyanomae, Syunan, Yamaguchi, 746-0017, Japan.
Sigeru SakanoDepartment of Urology, Kokura Memorial Hospital, 3-2-1 Asano, Kokura-ku, Kitakyusyu, Fukuoka, 802-8555, Japan.
Katsuhiko ImotoDepartment of Urology, Hikari Municipal Hikari General Hospital, 2-10-1 Nijigahama, Hikari, Yamaguchi, 743-0022, Japan.
Yasuhide TeiDepartment of Urology, Kanmon Medical Center, 1-1-1 Chofusotoura-cho, Shimonoseki, Yamaguchi, 752-8510, Japan.
Shiro YamaguchiDepartment of Urology, Shimonoseki Medical Center, 3-3-8 Kamishinchi-cho, Shimonoseki, Yamaguchi, 750-0061, Japan.
Seiji YanoDepartment of Urology, Ogori Daiichi General Hospital, 862-3 Ogori Shimogo, Yamaguchi, Yamaguchi, 754-0002, Japan.
Yamaguchi Uro-Onocology Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe standard of care for treatment of localized muscle-invasive bladder cancer (MIBC) is radical cystectomy (RC). The patient's condition may affect management of MIBC, especially for elderly patients with more comorbid conditions and lower performance status. We retrospectively evaluated the association between clinicopathological data and outcomes for patients with bladder cancer (BCa) treated by RC. We particularly focused on elderly patients (age ≥75 years) with BCa.

methodsWe enrolled 254 patients with BCa who underwent RC and urinary diversion with or without pelvic lymph node dissection. We assessed perioperative complications and clinicopathological data affecting overall survival (OS) after RC.

resultsThe incidence of complications was 34.3 %, and that of severe complications (Grade 3-5) was 16.5 %. The elderly group experienced more severe complications (P = 0.042). Median follow-up was 43.0 months (range 1.0-155.6). Five-year OS after RC was 62.7 %. OS after RC was no different for patients aged ≥75 and <75 years (P = 0.983). Multivariate analysis revealed that Eastern Cooperative Oncology Group performance status (ECOG PS) and hemoglobin (Hb) concentration were associated with all-cause mortality. Hb concentration of <12.6 g/dl was an independent predictor of a poor prognosis among elderly patients after RC for BCa. ECOG PS >1 tended to affect OS after RC in this group.

conclusionECOG PS and preoperative Hb concentration were useful for prediction of clinical outcome after RC for elderly patients. This information may aid decision-making in the treatment of elderly patients with MIBC.

Indexed as

Health StatusLymph Node ExcisionAdultAgedAged, 80 and overAge FactorsCystectomyFemaleFollow-Up StudiesHemoglobinsHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesHemoglobinsBladder cancerOverall survivalPatient selectionRadical cystectomy

Identifiers

PMID26077140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.