Trial reportIntensive care medicine2015
Electrical pharyngeal stimulation for dysphagia treatment in tracheotomized stroke patients: a randomized controlled trial.
Trial report in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 6 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Neuromuscular-related interventions for post-stroke dysphagia: a comprehensive narrative review.Frontiers in neuroscience · 2026Pooled it
- A Meta-Analysis and Systematic Review of the Effects of Sensory Modulation Treatments for Neurogenic Oropharyngeal Dysphagia.CNS neuroscience & therapeutics · 2025Pooled it
- Dysphagia Rehabilitation in Dysphagic Patients with Acute or Critical Illness: A Systematic Review and Meta-Analysis.Dysphagia · 2024Pooled it
- Interventions for oropharyngeal dysphagia in acute and critical care: a systematic review and meta-analysis.Intensive care medicine · 2020Pooled it
- Hypersalivation: update of the German S2k guideline (AWMF) in short form.Journal of neural transmission (Vienna, Austria : 1996) · 2019Guideline
- Swallowing therapy for dysphagia in acute and subacute stroke.The Cochrane database of systematic reviews · 2018Pooled it
- Pharyngeal electrical stimulation for postextubation dysphagia after stroke: a randomized trial on hospitalization costs from a health insurance perspective.Scientific reports · 2026Trial
- Metaplasticity in swallowing system via cross-modal neurostimulation: A randomized crossover trial with magnetoencephalography.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Trial
- Pharyngeal electrical stimulation to treat dysphagia in acute stroke: learnings from cases in the PhEED clinical trial.Journal of rehabilitation medicine · 2025Trial
- Treating postextubation dysphagia after stroke with pharyngeal electrical stimulation -insights from a randomized controlled pilot trial.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Trial
- Pharyngeal electrical stimulation for postextubation dysphagia in acute stroke: a randomized controlled pilot trial.Critical care (London, England) · 2023Trial
- Pharyngeal Electrical Stimulation for Treatment of Dysphagia in Subacute Stroke: A Randomized Controlled Trial.Stroke · 2016Trial
- Neuroanatomical organization: the palato-pharyngeal complex as a sensory-motor hub.Frontiers in neuroanatomy · 2026Review
- Brainstem Stroke and Dysphagia Treatment: A Narrative Review on the Role of Neuromodulation, Skill-Based Swallowing Training and Transient Receptor Potential Agonists.Audiology research · 2025Review
- Neurogenic Dysphagia: Peripheral and Central Neuromodulation.Clinics and practice · 2025Review
- Post-extubation dysphagia in the ICU-a narrative review: epidemiology, mechanisms and clinical management (Update 2025).Critical care (London, England) · 2025Review
- Clinical predictors of outcome after pharyngeal electrical stimulation (PES) in non-stroke related neurogenic dysphagia after mechanical ventilation and tracheotomy: results from subgroup analysis of PHADER study.Neurological research and practice · 2025Article
- Decannulation ahead: a comprehensive diagnostic and therapeutic framework for tracheotomized neurological patients.Neurological research and practice · 2025Review
- Research report: Management of dysphagia using pharyngeal electrical stimulation in the general intensive care population - A service development.Journal of the Intensive Care Society · 2024Article
- The Management of Sarcopenic Dysphagia: A Multidisciplinary Approach Leveraging Emerging Technologies.Aging and disease · 2024Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTreatment of post-stroke dysphagia is notoriously difficult with different neurostimulation strategies having been employed with a variable degree of success. Recently, electrical pharyngeal stimulation (EPS) has been shown to improve swallowing function and in particular decrease airway aspiration in acute stroke. We performed a randomized controlled trial to assess EPS effectiveness on swallowing function in severely dysphagic tracheotomized patients.
methodsAll consecutive stroke patients successfully weaned from the respirator but with severe dysphagia precluding decannulation were screened for eligibility. Eligible patients were randomized to receive either EPS (N = 20) or sham stimulation (N = 10) over three consecutive days. Primary endpoint was ability to decannulate the patient. Swallowing function was assessed using fiberoptic endoscopy. Patients having received sham stimulation were offered EPS treatment during unblinded follow-up if required. Investigators were blinded to the patient's study group allocation.
resultsBoth groups were well matched for age, stroke severity, and lesion location. Decannulation after study intervention was possible in 75% of patients of the treatment group and in 20% of patients of the sham group (p < 0.01). Secondary outcome parameters did not differ. No adverse events occurred.
conclusionIn this pilot study, EPS enhanced remission of dysphagia as assessed with fiberoptic endoscopic evaluation of swallowing (FEES), thereby enabling decannulation in 75% of patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.