Evidence map›Paper›PMID 26077053›Full record

GuidelineIntensive care medicine2015

Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).

Cédric Bretonnière, Marc Leone, Christophe Milési, Bernard Allaouchiche, Laurence Armand-Lefevre, Olivier Baldesi, Lila Bouadma, Dominique Decré, Samy Figueiredo, Rémy Gauzit and 17 more

Abstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Intensive care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Observational
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  12. Review
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  15. Article
  16. FDA approved antibacterial drugs: 2018-2019.Discoveries (Craiova, Romania) · 2019
    Review
  17. Risk factors for acquisition of carbapenem-resistance during treatment with carbapenem in the intensive care unit: a prospective study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Observational
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Cédric BretonnièreRéanimation Médicale Polyvalente, Pôle Hospitalo-Universitaire 3, CHU-Immeuble Jean Monnet, 44093, Nantes, France, cedric.bretonniere@chu-nantes.fr.
Marc Leone
Christophe Milési
Bernard Allaouchiche
Laurence Armand-Lefevre
Olivier Baldesi
Lila Bouadma
Dominique Decré
Samy Figueiredo
Rémy Gauzit
Benoît Guery
Nicolas Joram
Boris Jung
Sigismond Lasocki
Alain Lepape
Fabrice Lesage
Olivier Pajot
François Philippart
Bertrand Souweine
Pierre Tattevin
Jean-François Timsit
Renaud Vialet
Jean Ralph Zahar
Benoît Misset
Jean-Pierre Bedos
Société de Réanimation de Langue Française (SRLF)
Société Française d’Anesthésie et de Réanimation (SFAR)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging resistance to antibiotics shows no signs of decline. At the same time, few new antibacterials are being discovered. There is a worldwide recognition regarding the danger of this situation. The urgency of the situation and the conviction that practices should change led the Société de Réanimation de Langue Française (SRLF) and the Société Française d'Anesthésie et de Réanimation (SFAR) to set up a panel of experts from various disciplines. These experts met for the first time at the end of 2012 and have since met regularly to issue the following 67 recommendations, according to the rigorous GRADE methodology. Five fields were explored: i) the link between the resistance of bacteria and the use of antibiotics in intensive care; ii) which microbiological data and how to use them to reduce antibiotic consumption; iii) how should antibiotic therapy be chosen to limit consumption of antibiotics; iv) how can antibiotic administration be optimized; v) review and duration of antibiotic treatments. In each institution, the appropriation of these recommendations should arouse multidisciplinary discussions resulting in better knowledge of local epidemiology, rate of antibiotic use, and finally protocols for improving the stewardship of antibiotics. These efforts should contribute to limit the emergence of resistant bacteria.

Indexed as

Critical CareIntensive Care UnitsAnti-Bacterial AgentsBacterial InfectionsCross InfectionDrug MonitoringDrug Resistance, MicrobialHumansIntensive Care Units, PediatricUnnecessary ProceduresAnti-Bacterial Agents

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.