ReviewJournal of pathology and translational medicine2015
The Utilization of Cytologic Fine-Needle Aspirates of Lung Cancer for Molecular Diagnostic Testing.
Review in Journal of pathology and translational medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Article
- Biomarker testing of cytology specimens in personalized medicine for lung cancer patients.Journal of pathology and translational medicine · 2022Review
- False-negative programmed death-ligand 1 immunostaining in ethanol-fixed endobronchial ultrasound-guided transbronchial needle aspiration specimens of non-small-cell lung cancer patients.Histopathology · 2021Article
- Formalin fixation for optimal concordance of programmed death-ligand 1 immunostaining between cytologic and histologic specimens from patients with non-small cell lung cancer.Cancer cytopathology · 2021Article
- Influence of preanalytical variables on performance of delta-like protein 3 (DLL3) predictive immunohistochemistry.Virchows Archiv : an international journal of pathology · 2021Article
- The role of plasma genotyping in ALK- and ROS1-rearranged lung cancer.Translational lung cancer research · 2020Review
- Comparison of the SuperARMS and ARMS for detecting EGFR mutations in liquid-based cytology specimens from NSCLC patients.Diagnostic pathology · 2020Article
- The utilization of cytologic and small biopsy samples for ancillary molecular testing.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Review
- Salvaging the supernatant: next generation cytopathology for solid tumor mutation profiling.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2018Article
- Targeted next-generation sequencing in cytology specimens for molecular profiling of lung adenocarcinoma.International journal of clinical and experimental pathology · 2018Article
- Concurrent fine needle aspirations and core needle biopsies: a comparative study of substrates for next-generation sequencing in solid organ malignancies.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2017Article
- Next-generation molecular diagnosis: single-cell sequencing from bench to bedside.Cellular and molecular life sciences : CMLS · 2017Review
- Utilization of ancillary studies in the cytologic diagnosis of respiratory lesions: The papanicolaou society of cytopathology consensus recommendations for respiratory cytology.Diagnostic cytopathology · 2016Article
- Article
- Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this era of precision medicine, our understanding and knowledge of the molecular landscape associated with lung cancer pathogenesis continues to evolve. This information is being increasingly exploited to treat advanced stage lung cancer patients with tailored, targeted therapy. During the management of these patients, minimally invasive procedures to obtain samples for tissue diagnoses are desirable. Cytologic fine-needle aspirates are often utilized for this purpose and are important not only for rendering diagnoses to subtype patients' lung cancers, but also for ascertaining molecular diagnostic information for treatment purposes. Thus, cytologic fine-needle aspirates must be utilized and triaged judiciously to achieve both objectives. In this review, strategies in utilizing fine-needle aspirates will be discussed in the context of our current understanding of the clinically actionable molecular aberrations underlying non-small cell lung cancer and the molecular assays applied to these samples in order to obtain treatment-relevant molecular diagnostic information.
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