ArticleBMC genomics2015
Genome-wide transcriptomic analysis of a superior biomass-degrading strain of A. fumigatus revealed active lignocellulose-degrading genes.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- Microbial bioremediation of persistent organic pollutants in plant tissues provides crop growth promoting liquid fertilizer.Nature communications · 2025Article
- Harnessing Xylanase Potential inJournal of fungi (Basel, Switzerland) · 2025Article
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- Comparative genomic and transcriptome analysis of Bacillus velezensis CL-4 fermented corn germ meal.AMB Express · 2023Article
- Complete genome sequencing and investigation on the fiber-degrading potential of Bacillus amyloliquefaciens strain TL106 from the tibetan pig.BMC microbiology · 2022Article
- Fungal cellulases: protein engineering and post-translational modifications.Applied microbiology and biotechnology · 2022Review
- The Cultivation Method Affects the Transcriptomic Response of Aspergillus niger to Growth on Sugar Beet Pulp.Microbiology spectrum · 2021Article
- Microbial community dynamics in phyto-thermotherapy baths viewed through next generation sequencing and metabolomics approach.Scientific reports · 2020Article
- Variation Among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence AcrossGenetics · 2020Article
- Transcriptome Profiling-Based Analysis of Carbohydrate-Active Enzymes inFrontiers in bioengineering and biotechnology · 2020Article
- Microbe Profile: Aspergillus fumigatus: a saprotrophic and opportunistic fungal pathogen.Microbiology (Reading, England) · 2018Article
- Mixed evolutionary origins of endogenous biomass-depolymerizing enzymes in animals.BMC genomics · 2018Article
- Transcriptome and secretome analysis of Aspergillus fumigatus in the presence of sugarcane bagasse.BMC genomics · 2018Article
- Effect of CBM1 and linker region on enzymatic properties of a novel thermostable dimeric GH10 xylanase (Xyn10A) from filamentous fungus Aspergillus fumigatus Z5.AMB Express · 2018Article
- In Silico evaluation and identification of fungi capable of producing endo-inulinase enzyme.PloS one · 2018Article
- Analysis of the Transcriptome inFrontiers in bioengineering and biotechnology · 2018Article
- Secretion of small proteins is species-specific within Aspergillus sp.Microbial biotechnology · 2017Article
- Combined genome and transcriptome sequencing to investigate the plant cell wall degrading enzyme system in the thermophilic fungusBiotechnology for biofuels · 2017Article
- Extrolites of Aspergillus fumigatus and Other Pathogenic Species in Aspergillus Section Fumigati.Frontiers in microbiology · 2015Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious saprotrophic microorganisms, especially filamentous fungi, can efficiently degrade lignocellulose that is one of the most abundant natural materials on earth. It consists of complex carbohydrates and aromatic polymers found in the plant cell wall and thus in plant debris. Aspergillus fumigatus Z5 was isolated from compost heaps and showed highly efficient plant biomass-degradation capability.
resultsThe 29-million base-pair genome of Z5 was sequenced and 9540 protein-coding genes were predicted and annotated. Genome analysis revealed an impressive array of genes encoding cellulases, hemicellulases and pectinases involved in lignocellulosic biomass degradation. Transcriptional responses of A. fumigatus Z5 induced by sucrose, oat spelt xylan, Avicel PH-101 and rice straw were compared. There were 444, 1711 and 1386 significantly differently expressed genes in xylan, cellulose and rice straw, respectively, when compared to sucrose as a control condition.
conclusionsCombined analysis of the genomic and transcriptomic data provides a comprehensive understanding of the responding mechanisms to the most abundant natural polysaccharides in A. fumigatus. This study provides a basis for further analysis of genes shown to be highly induced in the presence of polysaccharide substrates and also the information which could prove useful for biomass degradation and heterologous protein expression.
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