ArticlePloS one2015
Lichen Simplex Chronicus Associated With Erectile Dysfunction: A Population-Based Retrospective Cohort Study.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- High prevalence of erectile dysfunction in men with psoriasis: evidence from a systematic review and meta-analysis.International journal of impotence research · 2019Pooled it
- Erectile dysfunction in dermatology and venereology: From aetiopathogenic mechanisms to practical considerations for dermato-venereologists.Journal of the European Academy of Dermatology and Venereology : JEADV · 2025Review
- Effectiveness of 0.1% mometasone furoate under hydrocolloid dressing versus 0.1% mometasone furoate in patients with lichen simplex chronicus.Skin health and disease · 2023Article
- Vulvar Neurodermatitis in a Postmenopausal African-American Patient: A Case Report.Journal of menopausal medicine · 2022Article
- Sexual Dysfunction and Atopic Dermatitis: A Systematic Review.Life (Basel, Switzerland) · 2021Review
- Article
- An intriguing case of lichen simplex chronicus in an elderly sub-Saharan African with longstanding scabies and sensory neuropathy.The Pan African medical journal · 2019Article
- Relationship between Erectile Dysfunction, Comorbidity, and Parkinson's Disease: Evidence from a Population-Based Longitudinal Study.Journal of clinical neurology (Seoul, Korea) · 2017Article
- Lichen Simplex Chronicus Secondary to Scald Injury and Skin Flap Transplantation.Indian journal of dermatologyArticle
- Psychosexual disorders and dermatologists.Indian dermatology online journalReview
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn association between lichen simplex chronicus (LSC) and sexual dysfunction was explored. However, no data are available from investigations into the relationship between erectile dysfunction (ED) and LSC.
objectivesThis retrospective population-based cohort study aimed to clarify the risk of ED associated with LSC.
methodsBy using the Taiwan National Health Insurance Research dataset, we identified 5611 male patients who had been newly diagnosed with LSC from 2000 to 2004. The date of diagnosis was identified as the index date. LSC patients with incomplete demographic information or with a history of ED before the index date were excluded. In total, 22444 age-matched patients without LSC were randomly selected as the non-LSC group based on a 1:4 ratio. Subsequence occurrence of ED was measured until 2011. The association between LSC and the risk of developing ED was estimated using Cox proportional hazard regression model.
resultsAfter adjusting for age and comorbidities, patients with LSC had a 1.74-fold greater risk of developing ED compared with those without LSC (95% confidence interval=1.44-2.10). LSC patients with comorbidities including diabetes, hyperlipidemia, hypertension, cardiovascular disease, peripheral arterial disease, chronic obstructive pulmonary disease, chronic kidney disease, depression, and anxiety were at a higher risk of ED compared with the non-LSC patients without comorbidities.
conclusionsLSC confers a greater risk in the development of ED. Physicians should be aware of the potential of ED occurrence in LSC patients.
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