ArticlePloS one2015
Non-Linear Concentration-Response Relationships between Ambient Ozone and Daily Mortality.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Air Quality Strategies on Public Health and Health Equity in Europe-A Systematic Review.International journal of environmental research and public health · 2016Pooled it
- Heat Exposure Following the Rainy Season Is Associated With an Increased Risk of Cardiovascular Emergency Among the Elderly in Japan.Journal of the American Heart Association · 2023Article
- Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR.The Science of the total environment · 2022Article
- Article
- Ozone Reacts With Carbon Black to Produce a Fulvic Acid-Like Substance and Increase an Inflammatory Effect.Toxicologic pathology · 2020Article
- Air pollutants disrupt iron homeostasis to impact oxidant generation, biological effects, and tissue injury.Free radical biology & medicine · 2020Review
- Short-term exposure to ambient air pollution and daily atherosclerotic heart disease mortality in a cool climate.Environmental science and pollution research international · 2019Article
- Current State of Research on the Risk of Morbidity and Mortality Associated with Air Pollution in Korea.Yonsei medical journal · 2019Review
- The toxicology of air pollution predicts its epidemiology.Inhalation toxicology · 2018Review
- Seasonal association between ambient ozone and hospital admission for respiratory diseases in Hanoi, Vietnam.PloS one · 2018Article
- Time series analysis of ambient air pollution effects on daily mortality.Environmental science and pollution research international · 2017Article
- Prenatal and postnatal bisphenol A exposure and social impairment in 4-year-old children.Environmental health : a global access science source · 2017Article
- Acute effect of ozone exposure on daily mortality in seven cities of Jiangsu Province, China: No clear evidence for threshold.Environmental research · 2017Article
- Association between Diurnal Variation of Ozone Concentration and Stroke Occurrence: 24-Hour Time Series Study.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAmbient ozone (O3) concentration has been reported to be significantly associated with mortality. However, linearity of the relationships and the presence of a threshold has been controversial.
objectivesThe aim of the present study was to examine the concentration-response relationship and threshold of the association between ambient O3 concentration and non-accidental mortality in 13 Japanese and Korean cities from 2000 to 2009.
methodsWe selected Japanese and Korean cities which have population of over 1 million. We constructed Poisson regression models adjusting daily mean temperature, daily mean PM10, humidity, time trend, season, year, day of the week, holidays and yearly population. The association between O3 concentration and mortality was examined using linear, spline and linear-threshold models. The thresholds were estimated for each city, by constructing linear-threshold models. We also examined the city-combined association using a generalized additive mixed model.
resultsThe mean O3 concentration did not differ greatly between Korea and Japan, which were 26.2 ppb and 24.2 ppb, respectively. Seven out of 13 cities showed better fits for the spline model compared with the linear model, supporting a non-linear relationships between O3 concentration and mortality. All of the 7 cities showed J or U shaped associations suggesting the existence of thresholds. The range of city-specific thresholds was from 11 to 34 ppb. The city-combined analysis also showed a non-linear association with a threshold around 30-40 ppb.
conclusionWe have observed non-linear concentration-response relationship with thresholds between daily mean ambient O3 concentration and daily number of non-accidental death in Japanese and Korean cities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.