ArticlePloS one2015
Identification of Novel SNP in Promoter Sequence of TaGW2-6A Associated with Grain Weight and Other Agronomic Traits in Wheat (Triticum aestivum L.).
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40 citing papers in PubMed, 67 citations in OpenAlex.
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- Wheat improvement through advances in single nucleotide polymorphism (SNP) detection and genotyping with a special emphasis on rust resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Deciphering the differential expression patterns of yield-related negative regulators in hexaploid wheat cultivars and hybrids at different growth stages.Molecular biology reports · 2024Article
- Fine mapping of a major QTL, qKl-1BL controlling kernel length in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Precisely mapping a major QTL for grain weight on chromosome 5B of the founder parent Chuanmai42 in the wheat-growing region of southwestern China.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Genome-Wide Tissue-Specific Genes Identification for Novel Tissue-Specific Promoters Discovery in Soybean.Genes · 2023Article
- Genetic Localization and Homologous Genes Mining for Barley Grain Size.International journal of molecular sciences · 2023Review
- Genome-wide association analysis of spike and kernel traits in the U.S. hard winter wheat.The plant genome · 2023Article
- Genetic dissection of major QTL for grain number per spike on chromosomes 5A and 6A in bread wheat (Frontiers in plant science · 2023Article
- Fine mapping and characterization of a major QTL for grain weight on wheat chromosome arm 5DL.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Genes Impacting Grain Weight and Number in Wheat (Plants (Basel, Switzerland) · 2022Review
- N6-Methyladenosine dynamic changes and differential methylation in wheat grain development.Planta · 2022Article
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- Quantitative trait loci identification and breeding value estimation of grain weight-related traits based on a new wheat 50K single nucleotide polymorphism array-derived genetic map.Frontiers in plant science · 2022Article
- In Silico Identification of the Complex Interplay between Regulatory SNPs, Transcription Factors, and Their Related Genes inInternational journal of molecular sciences · 2021Article
- Mapping QTL for agronomic traits under two levels of salt stress in a new constructed RIL wheat population.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Genetic Mapping by Integration of 55K SNP Array and KASP Markers Reveals Candidate Genes for Important Agronomic Traits in Hexaploid Wheat.Frontiers in plant science · 2021Article
- RING finger ubiquitin E3 ligase gene TaSDIR1-4A contributes to determination of grain size in common wheat.Journal of experimental botany · 2020Article
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Authors and funding
9 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
TaGW2 is an orthologue of rice gene OsGW2, which encodes E3 RING ubiquitin ligase and controls the grain size in rice. In wheat, three copies of TaGW2 have been identified and mapped on wheat homoeologous group 6 viz. TaGW2-6A, TaGW2-6B and TaGW2-6D. In the present study, using as many as 207 Indian wheat genotypes, we identified four SNPs including two novel SNPs (SNP-988 and SNP-494) in the promoter sequence of TaGW2-6A. All the four SNPs were G/A or A/G substitutions (transitions). Out of the four SNPs, SNP-494 was causal, since it was found associated with grain weight. The mean TGW (41.1 g) of genotypes with the allele SNP-494_A was significantly higher than mean TGW (38.6 g) of genotypes with the allele SNP-494_G. SNP-494 also regulates the expression of TaGW2-6A so that the wheat genotypes with SNP-494_G have higher expression and lower TGW and the genotypes with SNP-494_A have lower expression but higher TGW. Besides, SNP-494 was also found associated with grain length-width ratio, awn length, spike length, grain protein content, peduncle length and plant height. This suggested that gene TaGW2-6A not only controls grain size, but also controls other agronomic traits. In the promoter region, SNP-494 was present in 'CGCG' motif that plays an important role in Ca2+/calmodulin mediated regulation of genes. A user-friendly CAPS marker was also developed to identify the desirable allele of causal SNP (SNP-494) for use in marker-assisted selection for improvement of grain weight in wheat. Using four SNPs, five haplotypes were identified; of these, Hap_5 (G_A_G_A) was found to be a desirable haplotype having significantly higher grain weight (41.13g) relative to other four haplotypes (36.33-39.16 g).
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