Evidence map›Paper›PMID 26076097›Full record

ArticlePsychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors2015

Prenatal substance exposure: What predicts behavioral resilience by early adolescence?

Jane M Liebschutz, Denise Crooks, Ruth Rose-Jacobs, Howard J Cabral, Timothy C Heeren, Jessie Gerteis, Danielle P Appugliese, Orlaith D Heymann, Allison V Lange, Deborah A Frank

Abstract read
In one paragraph

Article in Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jane M LiebschutzClinical Addiction Research and Education Unit, Boston Medical Center.
Denise CrooksDepartment of Family Medicine, Boston Medical Center.
Ruth Rose-JacobsDepartment of Pediatrics, Boston Medical Center.
Howard J CabralDepartment of Biostatistics, Boston University School of Public Health.
Timothy C HeerenData Coordinating Center, Boston University School of Public Health.
Jessie GerteisAbt Associates, Inc.
Danielle P AppuglieseData Coordinating Center, Boston University School of Public Health.
Orlaith D HeymannClinical Addiction Research and Education Unit, Boston Medical Center.
Allison V LangeClinical Addiction Research and Education Unit, Boston Medical Center.
Deborah A FrankDepartment of Family Medicine, Boston Medical Center.

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
YOGA INDUCED CHANGES IN BRAIN GABA LEVELSM01RR000533 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HOLICK, MICHAEL F. · 1985 to 2008
$19.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025771 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2008 to 2011
$17.6M
Prenatal Cocaine Exposure: Young Adult Follow UpR01DA006532 · NIDA · BOSTON MEDICAL CENTER · PI FRANK, DEBORAH A, LIEBSCHUTZ, JANE M · 1990 to 2014
$12.4M
NCRR NIH HHS M01 RR000533NCRR NIH HHS RR000533NCRR NIH HHS RR025771NCRR NIH HHS UL1 RR025771NICHD NIH HHS P01 HD031921NIDA NIH HHS DA 06532NIDA NIH HHS R01 DA006532
6 · The paper itself

Abstract

Understanding behavioral resilience among at-risk adolescents may guide public policy decisions and future programs. We examined factors predicting behavioral resilience following intrauterine substance exposure in a prospective longitudinal birth-cohort study of 136 early adolescents (ages 12.4-15.9 years) at risk for poor behavioral outcomes. We defined behavioral resilience as a composite measure of lack of early substance use initiation (before age 14), lack of risky sexual behavior, or lack of delinquency. Intrauterine substance exposures included in this analysis were cocaine, tobacco, alcohol, and marijuana. We recruited participants from Boston Medical Center as mother-infant dyads between 1990 and 1993. The majority of the sample was African American/Caribbean (88%) and 49% female. In bivariate analyses, none and lower intrauterine cocaine exposure level predicted resilience compared with higher cocaine exposure, but this effect was not found in an adjusted model. Instead, strict caregiver supervision (adjusted odds ratio [AOR] = 6.02, 95% confidence interval (CI) [1.90, 19.00], p = .002), lower violence exposure (AOR = 4.07, 95% CI [1.77, 9.38], p < .001), and absence of intrauterine tobacco exposure (AOR = 3.71, 95% CI [1.28, 10.74], p = .02) predicted behavioral resilience. In conclusion, caregiver supervision in early adolescence, lower violence exposure in childhood, and lack of intrauterine tobacco exposure predicted behavioral resilience among a cohort of early adolescents with significant social and environmental risk. Future interventions should work to enhance parental supervision as a way to mitigate the effects of adversity on high-risk groups of adolescents. (PsycINFO Database Record

Indexed as

Adolescent BehaviorCannabisCocaineEthanolParentingPrenatal Exposure Delayed EffectsResilience, PsychologicalViolenceAdolescentChildFemaleHumansLongitudinal StudiesMalePregnancyTobacco Smoke PollutionCocaineEthanolTobacco Smoke Pollution

Identifiers

PMID26076097
PMCPMC4593628

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.