Evidence map›Paper›PMID 26075888›Full record

ArticlePloS one2015

A Cost Analysis of Hospitalizations for Infections Related to Injection Drug Use at a County Safety-Net Hospital in Miami, Florida.

Hansel Tookes, Chanelle Diaz, Hua Li, Rafi Khalid, Susanne Doblecki-Lewis

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04544306 (Partial Oral Antimicrobial Versus Intravenous Antimicrobial Therapy to Treat Infective Endocarditis in People Who Inject Drugs), which is not on this map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04544306 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Partial Oral Antimicrobial Versus Intravenous Antimicrobial Therapy to Treat Infective Endocarditis in People Who Inject Drugs

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2021 to 2025Enrolled50ConditionsInfective EndocarditisArmsPartial oral antimicrobial therapy
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Drug Use and Postoperative Mortality Following Valve Surgery for Infective Endocarditis: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Pooled it
  5. Review
  6. Article
  7. Observational
  8. Ethical Management of Challenging Behaviors in Hospitalized People Who Use Drugs.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Patterns of Infectious Disease Associated With Injection Drug Use in Massachusetts.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hansel TookesDepartment of Internal Medicine, Jackson Memorial Hospital, Miami, Florida, United States of America.
Chanelle DiazDepartment of Medical Education, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Hua LiDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
Rafi KhalidDepartment of Jackson Health System Research, Jackson Memorial Hospital, Miami, Florida, United States of America.
Susanne Doblecki-LewisDepartment of Internal Medicine, Division of Infectious Diseases, University of Miami Miller School of Medicine, Miami, Florida, United States of America.
University of Miami · USJackson Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfections related to injection drug use are common. Harm reduction strategies such as syringe exchange programs and skin care clinics aim to prevent these infections in injection drug users (IDUs). Syringe exchange programs are currently prohibited by law in Florida. The goal of this study was to estimate the mortality and cost of injection drug use-related bacterial infections over a 12-month period to the county safety-net hospital in Miami, Florida. Additionally, the prevalence of HIV and hepatitis C virus among this cohort of hospitalized IDUs was estimated. METHODS AND

findingsIDUs discharged from Jackson Memorial Hospital were identified using the International Classification of Diseases, Ninth Revision, codes for illicit drug abuse and endocarditis, bacteremia or sepsis, osteomyelitis and skin and soft tissue infections (SSTIs). 349 IDUs were identified for chart abstraction and 92% were either uninsured or had publicly funded insurance. SSTIs, the most common infection, were reported in 64% of IDUs. HIV seroprevalence was 17%. Seventeen patients (4.9%) died during their hospitalization. The total cost for treatment for injection drug use-related infections to Jackson Memorial Hospital over the 12-month period was $11.4 million.

conclusionsInjection drug use-related bacterial infections represent a significant morbidity for IDUs in Miami-Dade County and a substantial financial cost to the county hospital. Strategies aimed at reducing risk of infections associated with injection drug use could decrease morbidity and the cost associated with these common, yet preventable infections.

Indexed as

Costs and Cost AnalysisDrug UsersHospitalizationSafety-net ProvidersAdolescentAdultAgedFemaleFloridaHumansInfectionsMaleMiddle AgedRetrospective StudiesSubstance Abuse, IntravenousYoung Adult

Identifiers

PMID26075888
PMCPMC4468183
OpenAlexW584648207

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.