Evidence map›Paper›PMID 26075001›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2015

Antithrombotic Effects of Five Organic Extracts of Bangladeshi Plants In Vitro and Mechanisms in In Silico Models.

Sakib Mahmud, Samina Akhter, Md Atiar Rahman, Jannatul Aklima, Shaheen Akhter, Syeeda Rayhana Merry, S M Rakibul Jubair, Raju Dash, Talha Bin Emran

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. In Vitro Antilipidic and Antithrombotic Activities ofBioMed research international · 2022
    Article
  4. Article
  5. Oxidative medicine and cellular longevity · 2020
    Article
  6. Effects ofEvidence-based complementary and alternative medicine : eCAM · 2018
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sakib MahmudDepartment of Biochemistry and Molecular Biology, University of Chittagong, Chittagong 4331, Bangladesh.
Samina AkhterDepartment of Biochemistry and Molecular Biology, University of Chittagong, Chittagong 4331, Bangladesh.
Md Atiar RahmanDepartment of Biochemistry and Molecular Biology, University of Chittagong, Chittagong 4331, Bangladesh.
Jannatul AklimaDepartment of Biochemistry and Molecular Biology, University of Chittagong, Chittagong 4331, Bangladesh.
Shaheen AkhterBangladesh Forest Research Institute, Chittagong 4000, Bangladesh.
Syeeda Rayhana MerryBangladesh Forest Research Institute, Chittagong 4000, Bangladesh.
S M Rakibul JubairBangladesh Forest Research Institute, Chittagong 4000, Bangladesh.
Raju DashDepartment of Pharmacy, BGC Trust University, Chittagong 4000, Bangladesh.
Talha Bin EmranDepartment of Pharmacy, BGC Trust University, Chittagong 4000, Bangladesh.
University of Chittagong · BDBGC Trust University Bangladesh · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research was carried out to investigate the thrombolytic effects of the methanolic extracts of five Bangladeshi plants. Phytochemical metabolites of those plants have been identified to elucidate whether the plant-derived metabolites are linked with the thrombolytic effects. Potential computer aided models were adopted in this study to find out a structure-function correlation between the phytochemical constituents and thrombolytic effects using the secondary metabolites as ligands and tissue plasminogen activator (t-PA) as receptor for the best fit ligand-receptor interaction.

Identifiers

PMID26075001
PMCPMC4449917
OpenAlexW1546883557

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.