Evidence map›Paper›PMID 26074807›Full record

ArticleFrontiers in human neuroscience2015

The relevance of aging-related changes in brain function to rehabilitation in aging-related disease.

Bruce Crosson, Keith M McGregor, Joe R Nocera, Jonathan H Drucker, Stella M Tran, Andrew J Butler

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. tDCS-Induced Modulation of GABA Levels and Resting-State Functional Connectivity in Older Adults.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Trial
  3. Review
  4. Review
  5. Article
  6. Neuromodulation in post-stroke aphasia treatment.Current physical medicine and rehabilitation reports · 2020
    Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bruce CrossonDepartment of Veterans Affairs Rehabilitation Research and Development Center of Excellence for Visual and Neurocognitive Rehabilitation (151R), Atlanta VA Medical Center Decatur, GA, USA ; Department of Neurology, Emory University Atlanta, GA, USA ; Department of Psychology, Georgia State University Atlanta, GA, USA ; School of Health and Rehabilitation Sciences, University of Queensland Brisbane, Qld, Australia.
Keith M McGregorDepartment of Veterans Affairs Rehabilitation Research and Development Center of Excellence for Visual and Neurocognitive Rehabilitation (151R), Atlanta VA Medical Center Decatur, GA, USA ; Department of Neurology, Emory University Atlanta, GA, USA.
Joe R NoceraDepartment of Veterans Affairs Rehabilitation Research and Development Center of Excellence for Visual and Neurocognitive Rehabilitation (151R), Atlanta VA Medical Center Decatur, GA, USA ; Department of Neurology, Emory University Atlanta, GA, USA.
Jonathan H DruckerDepartment of Veterans Affairs Rehabilitation Research and Development Center of Excellence for Visual and Neurocognitive Rehabilitation (151R), Atlanta VA Medical Center Decatur, GA, USA ; Department of Neurology, Emory University Atlanta, GA, USA ; Department of Psychology, Emory University Atlanta, GA, USA.
Stella M TranDepartment of Veterans Affairs Rehabilitation Research and Development Center of Excellence for Visual and Neurocognitive Rehabilitation (151R), Atlanta VA Medical Center Decatur, GA, USA ; Department of Psychology, Georgia State University Atlanta, GA, USA.
Andrew J ButlerDepartment of Veterans Affairs Rehabilitation Research and Development Center of Excellence for Visual and Neurocognitive Rehabilitation (151R), Atlanta VA Medical Center Decatur, GA, USA ; Department of Physical Therapy and School of Nursing and Health Professionals, Georgia State University Atlanta, GA, USA.

Funding

Effects of exercise intervention on aging-related motor declineIK2RX000956 · VA · VETERANS HEALTH ADMINISTRATION · PI MCGREGOR, KEITH MATTHEW · 2015 to 2017
–
RRD VA IK2 RX000956
6 · The paper itself

Abstract

The effects of aging on rehabilitation of aging-related diseases are rarely a design consideration in rehabilitation research. In this brief review we present strong coincidental evidence from these two fields suggesting that deficits in aging-related disease or injury are compounded by the interaction between aging-related brain changes and disease-related brain changes. Specifically, we hypothesize that some aphasia, motor, and neglect treatments using repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) in stroke patients may address the aging side of this interaction. The importance of testing this hypothesis and addressing the larger aging by aging-related disease interaction is discussed. Underlying mechanisms in aging that most likely are relevant to rehabilitation of aging-related diseases also are covered.

Indexed as

agingaphasiahemiplegianeuroimagingrehabilitationstroketranscranial direct current stimulationtranscranial magnetic stimulation repetitive

Identifiers

PMID26074807
PMCPMC4444823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.