ReviewWorld journal of gastroenterology2015
Nocardia infections among immunomodulated inflammatory bowel disease patients: A review.
Review in World journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 66 citations in OpenAlex.
- Secreted protein NFA47630 from Nocardia farcinica IFM10152 induces immunoprotective effects in mice.Tropical diseases, travel medicine and vaccines · 2024Article
- [Acute abdomen-Rare cause in an 80-year-old female patient under immunosuppressive treatment].Innere Medizin (Heidelberg, Germany) · 2024Article
- A Rare Case Report of Disseminated Nocardia Farcinica Granulomatous Hepatitis and Clinical Management Experience.Infection and drug resistance · 2024Article
- A case of nocardiosis in a patient with ulcerative colitis on chronic corticosteroids, infliximab, and upadacitinib.Clinical case reports · 2023Article
- A case report on mixed pulmonary infection ofFrontiers in public health · 2022Article
- A Rare Case of Co-Infection withInfection and drug resistance · 2022Article
- Disseminated Nocardia farcinica involves the spinal cord: a case report and review of the literature.BMC infectious diseases · 2021Review
- Primary cutaneous nocardiosis caused byIDCases · 2021Article
- Clinical analysis of 11 cases of nocardiosis.Open medicine (Warsaw, Poland) · 2021Article
- Efficient differentiation ofJournal of medical microbiology · 2020Article
- Diagnosis of severe respiratory infections in immunocompromised patients.Intensive care medicine · 2020Review
- Opportunistic Infections Are More Prevalent in Crohn's Disease and Ulcerative Colitis: A Large Population-Based Study.Inflammatory bowel diseases · 2020Article
- Nocardia farcinica isolated meningitis in a patient with Behçet's disease: case report and literature review.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2019Review
- An unusual calf lesion in an immunocompromised patient.Internal and emergency medicine · 2019Article
- Isolation and characterization of bacteriophage NTR1 infectious for Nocardia transvalensis and other Nocardia species.Virus genes · 2019Article
- Pathogenic Nocardia cyriacigeorgica and Nocardia nova Evolve To Resist Trimethoprim-Sulfamethoxazole by both Expected and Unexpected Pathways.Antimicrobial agents and chemotherapy · 2018Article
- Disseminated Nocardiosis Associated with Treatment with Infliximab in a Patient with Ulcerative Colitis.The American journal of case reports · 2017Article
- Primary Cutaneous Nocardiosis in a Patient Taking Adalimumab Therapy for Crohn's Disease.Kansas journal of medicine · 2017Article
- Virulence test using nematodes to prescreenPeerJ · 2017Article
- Central nervous system nocardiosis in Queensland: A report of 20 cases and review of the literature.Medicine · 2016Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human nocardiosis, caused by Nocardia spp., an ubiquitous soil-borne bacteria, is a rare granulomatous disease close related to immune dysfunctions. Clinically can occur as an acute life-threatening disease, with lung, brain and skin being commonly affected. The infection was classically diagnosed in HIV infected persons, organ transplanted recipients and long term corticosteroid treated patients. Currently the widespread use of immunomodulators and immunossupressors in the treatment of inflammatory diseases changed this scenario. Our purpose is to review all published cases of nocardiosis in immunomodulated patients due to inflammatory diseases and describe clinical and laboratory findings. We reviewed the literature concerning human cases of nocardiosis published between 1980 and 2014 in peer reviewed journals. Eleven cases of nocardiosis associated with anti-tumor necrosis factor (TNF) prescription (9 related with infliximab and 2 with adalimumab) were identified; 7 patients had inflammatory bowel disease (IBD), 4 had rheumatological conditions; nocardia infection presented as cutaneous involvement in 3 patients, lung disease in 4 patients, hepatic in one and disseminated disease in 3 patients. From the 10 cases described in IBD patients 7 were associated with anti-TNF and 3 with steroids and azathioprine. In conclusion, nocardiosis requires high levels of clinical suspicion and experience of laboratory staff, in order to establish a timely diagnosis and by doing so avoid worst outcomes. Treatment for long periods tailored by the susceptibility of the isolated species whenever possible is essential. The safety of restarting immunomodulators or anti-TNF after the disease or the value of prophylaxis with cotrimoxazole is still debated.
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